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Association Between Anthropometric Markers of Adiposity, Adipokines and Vitamin D Levels

Overview
Journal Sci Rep
Specialty Science
Date 2022 Sep 14
PMID 36104384
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Abstract

Inverse association between serum levels of vitamin D and obesity has been pointed out in several studies. Our aim was to identify to the associations between vitamin D levels and a large panel of anthropometric markers and adipokines. Cross-sectional study including 6485 participants. Anthropometric markers included body mass index (BMI), % body fat, waist, waist-to-hip (WHR), waist-to-height (WHtR), conicity index, body roundness index (BRI) and a body shape index (ABSI). 55.7% of women and 60.1% of men presented with vitamin D deficiency. Vitamin D levels were negatively associated with most anthropometric markers, with correlation coefficients ranging between -0.017 (ABSI) and -0.192 (BMI) in women and between -0.026 (weight) and -0.130 (% body fat) in men. Vitamin D levels were inversely associated with leptin levels in both sexes and positively associated with adiponectin levels in women only. The likelihood of vitamin D deficiency increased with increasing adiposity levels, except for ABSI (women) and BMI (men). Total body fat, rather than localized or unevenly distributed body fat, is the adiposity marker most associated with decreased vitamin D levels. Monitoring vitamin D levels in people with overweight/obesity is essential.

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The Role of Maternal Vitamin D Deficiency in Offspring Obesity: A Narrative Review.

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References
1.
Gangloff A, Bergeron J, Lemieux I, Tremblay A, Poirier P, Almeras N . Relationships between circulating 25(OH) vitamin D, leptin levels and visceral adipose tissue volume: results from a 1-year lifestyle intervention program in men with visceral obesity. Int J Obes (Lond). 2019; 44(2):280-288. DOI: 10.1038/s41366-019-0347-7. View

2.
Gangloff A, Bergeron J, Lemieux I, Despres J . Changes in circulating vitamin D levels with loss of adipose tissue. Curr Opin Clin Nutr Metab Care. 2016; 19(6):464-470. DOI: 10.1097/MCO.0000000000000315. View

3.
Holick M, Binkley N, Bischoff-Ferrari H, Gordon C, Hanley D, Heaney R . Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab. 2011; 96(7):1911-30. DOI: 10.1210/jc.2011-0385. View

4.
Savastano S, Barrea L, Savanelli M, Nappi F, Di Somma C, Orio F . Low vitamin D status and obesity: Role of nutritionist. Rev Endocr Metab Disord. 2017; 18(2):215-225. DOI: 10.1007/s11154-017-9410-7. View

5.
Holick M . The vitamin D deficiency pandemic: Approaches for diagnosis, treatment and prevention. Rev Endocr Metab Disord. 2017; 18(2):153-165. DOI: 10.1007/s11154-017-9424-1. View