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Factors Associated with Inadequate Treatment of Syphilis During Pregnancy: an Integrative Review

Overview
Journal Rev Bras Enferm
Specialty Nursing
Date 2022 Sep 14
PMID 36102473
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Abstract

Objectives: to analyze the evidence available in literature on factors associated with inadequate treatment of syphilis in pregnant women.

Methods: an integrative review, carried out in the LILACS, CINAHL, Web of Science, Scopus, PubMed and EMBASE databases, with controlled descriptors therapeutic and prenatal syphilis.

Results: nine publications composed the interpretative analysis, in which low education, income and maternal age, temporary lack of medication and HIV infection were associated with inadequate treatment of syphilis during pregnancy, in addition to delay or absence of prenatal care and receiving the 1st dose of penicillin, lack of tests or treatment less than 30 days before childbirth, and partners' low compliance with treatment.

Final Considerations: among the main factors associated with inadequate treatment, clinical and sociodemographic aspects stand out, as well as failures in drug dispensing, prescription and monitoring of treatment of pregnant women and their partners by the health system.

References
1.
Ganong L . Integrative reviews of nursing research. Res Nurs Health. 1987; 10(1):1-11. DOI: 10.1002/nur.4770100103. View

2.
Korenromp E, Rowley J, Alonso M, Mello M, Wijesooriya N, Mahiane S . Global burden of maternal and congenital syphilis and associated adverse birth outcomes-Estimates for 2016 and progress since 2012. PLoS One. 2019; 14(2):e0211720. PMC: 6392238. DOI: 10.1371/journal.pone.0211720. View

3.
Rahman M, Hoover A, Johnson C, Peterman T . Preventing Congenital Syphilis-Opportunities Identified by Congenital Syphilis Case Review Boards. Sex Transm Dis. 2018; 46(2):139-142. PMC: 10158818. DOI: 10.1097/OLQ.0000000000000909. View

4.
Kidd S, Bowen V, Torrone E, Bolan G . Use of National Syphilis Surveillance Data to Develop a Congenital Syphilis Prevention Cascade and Estimate the Number of Potential Congenital Syphilis Cases Averted. Sex Transm Dis. 2018; 45(9S Suppl 1):S23-S28. PMC: 6737534. DOI: 10.1097/OLQ.0000000000000838. View

5.
Anugulruengkitt S, Yodkitudomying C, Sirisabya A, Chitsinchayakul T, Jantarabenjakul W, Chaithongwongwatthana S . Gaps in the elimination of congenital syphilis in a tertiary care center in Thailand. Pediatr Int. 2019; 62(3):330-336. DOI: 10.1111/ped.14132. View