Synthesis and Activity of Ionic Antioxidant-Functionalized PAMAMs and PPIs Dendrimers

Overview

Journal Polymers (Basel)

Publisher MDPI

Date 2022 Sep 9

PMID 36080588

Authors

Katia Bacha

Julien Estager

Sylvie Brassart-Pasco

Catherine Chemotti

Antony E Fernandes

Jean-Pierre Mbakidi

Magali Deleu

Sandrine Bouquillon

Affiliations

Soon will be listed here.

Abstract

For this study, new dendrimers were prepared from poly(propylene imine) (PPI) and polyamidoamine (PAMAM) dendrimers using an efficient acid-base reaction with various phenolic acids. The syntheses were also optimized in both microwave and microfluidic reactors. These ionic and hydrophilic dendrimers were fully characterized and showed excellent antioxidant properties. Their cytotoxic properties have been also determined in the case of fibroblast dermal cells.

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