When Autoimmunity 'DRESSes Up': A Case After Certolizumab Therapy

Overview

Journal Eur J Case Rep Intern Med

Specialty General Medicine

Date 2022 Sep 2

PMID 36051169

Authors

Benedetta Marigliano

Federico Rosa

Mattia Internullo

Luigi Scuro

Andrea Tavanti

Lucia Rita Del Vecchio

Francesco Paolo Romagno

Maria Barbara Schito

Federica Pace

Giovanni Maria Colombo

Emanuele Guglielmelli

Affiliations

Soon will be listed here.

Abstract

Learning Points: Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) is an uncommon and under-reported syndrome.Its recognition is critical for treatment, especially in the emergency setting where most patients first present.In the case of unexplained fever, lymphadenopathy, cutaneous rash and characteristic laboratory findings (e.g., eosinophilia), after infectious causes have been ruled out, clinicians should always keep DRESS in mind and consider possible recent intake of a triggering drug.

References

Bocquet H, Bagot M, Roujeau J . Drug-induced pseudolymphoma and drug hypersensitivity syndrome (Drug Rash with Eosinophilia and Systemic Symptoms: DRESS). Semin Cutan Med Surg. 1996; 15(4):250-7. DOI: 10.1016/s1085-5629(96)80038-1. View

Wolfson A, Zhou L, Li Y, Phadke N, Chow O, Blumenthal K . Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) Syndrome Identified in the Electronic Health Record Allergy Module. J Allergy Clin Immunol Pract. 2018; 7(2):633-640. PMC: 6363826. DOI: 10.1016/j.jaip.2018.08.013. View

Knowles S, SHAPIRO L, Shear N . Anticonvulsant hypersensitivity syndrome: incidence, prevention and management. Drug Saf. 1999; 21(6):489-501. DOI: 10.2165/00002018-199921060-00005. View

Chen Y, Chiu H, Chu C . Drug reaction with eosinophilia and systemic symptoms: a retrospective study of 60 cases. Arch Dermatol. 2010; 146(12):1373-9. DOI: 10.1001/archdermatol.2010.198. View

Chiou C, Yang L, Hung S, Chang Y, Kuo T, Ho H . Clinicopathological features and prognosis of drug rash with eosinophilia and systemic symptoms: a study of 30 cases in Taiwan. J Eur Acad Dermatol Venereol. 2008; 22(9):1044-9. DOI: 10.1111/j.1468-3083.2008.02585.x. View

Tetart F, Picard D, Janela B, Joly P, Musette P . Prolonged evolution of drug reaction with eosinophilia and systemic symptoms: clinical, virologic, and biological features. JAMA Dermatol. 2013; 150(2):206-7. DOI: 10.1001/jamadermatol.2013.6698. View

Shiohara T, Kano Y . Drug reaction with eosinophilia and systemic symptoms (DRESS): incidence, pathogenesis and management. Expert Opin Drug Saf. 2016; 16(2):139-147. DOI: 10.1080/14740338.2017.1270940. View

Leman R, Chen L, Shi X, Rolimpandoei S, Ling X, Su Y . Drug reaction with eosinophilia and systemic symptoms (DRESS) successfully treated with tumor necrosis factor-α inhibitor. JAAD Case Rep. 2017; 3(4):332-335. PMC: 5518151. DOI: 10.1016/j.jdcr.2017.05.006. View

Lin I, Yang H, Strong C, Yang C, Cho Y, Chen K . Liver injury in patients with DRESS: A clinical study of 72 cases. J Am Acad Dermatol. 2015; 72(6):984-91. DOI: 10.1016/j.jaad.2015.02.1130. View

10.

Descamps V, Ben Said B, Sassolas B, Truchetet F, Avenel-Audran M, Girardin P . [Management of drug reaction with eosinophilia and systemic symptoms (DRESS)]. Ann Dermatol Venereol. 2010; 137(11):703-8. DOI: 10.1016/j.annder.2010.04.024. View

11.

Wu X, Yang F, Chen S, Xiong H, Zhu Q, Gao X . Clinical, Viral and Genetic Characteristics of Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) in Shanghai, China. Acta Derm Venereol. 2017; 98(4):401-405. DOI: 10.2340/00015555-2867. View

12.

Kardaun S, Sekula P, Valeyrie-Allanore L, Liss Y, Chu C, Creamer D . Drug reaction with eosinophilia and systemic symptoms (DRESS): an original multisystem adverse drug reaction. Results from the prospective RegiSCAR study. Br J Dermatol. 2013; 169(5):1071-80. DOI: 10.1111/bjd.12501. View

13.

Morrisroe K, Wong M . Drug-induced hypereosinophilia related to tocilizumab therapy for rheumatoid arthritis. Rheumatology (Oxford). 2015; 54(11):2113-4. DOI: 10.1093/rheumatology/kev275. View

14.

Descamps V, Valance A, Edlinger C, Fillet A, Grossin M, Lebrun-Vignes B . Association of human herpesvirus 6 infection with drug reaction with eosinophilia and systemic symptoms. Arch Dermatol. 2001; 137(3):301-4. View

15.

Chowdhury M, Azari B, Desai N, Ahmad T . A Novel Treatment for a Rare Cause of Cardiogenic Shock. JACC Case Rep. 2021; 2(10):1461-1465. PMC: 8302098. DOI: 10.1016/j.jaccas.2020.02.004. View

16.

Cho Y, Yang C, Chu C . Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS): An Interplay among Drugs, Viruses, and Immune System. Int J Mol Sci. 2017; 18(6). PMC: 5486066. DOI: 10.3390/ijms18061243. View