Enzyme-catalyzed Allylic Oxidation Reactions: A Mini-review

Overview

Journal Front Chem

Specialty Chemistry

Date 2022 Sep 1

PMID 36046724

Authors

Maoyao Wang

Xiaojian Zhou

Zhongqiang Wang

Yongzheng Chen

Affiliations

Soon will be listed here.

Abstract

Chiral allylic oxidized products play an increasingly important role in the pharmaceutical, agrochemical, and pharmaceutical industries. Biocatalytic C-H oxyfunctionalization to synthesize allylic oxidized products has attracted great attention in recent years, with the ability to simplify synthetic approaches toward complex compounds. As a result, scientists have found some new enzymes and mutants through techniques of gene mining and enzyme-directed evolution in recent years. This review summarizes the recent developments in biocatalytic selective oxidation of olefins by different kinds of biocatalysts.

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