The Effect of the Lunar Cycle on Migraine: Preliminary Findings from a Retrospective Study

Overview

Journal Acta Neurol Belg

Publisher Springer

Specialty Neurology

Date 2022 Aug 27

PMID 36029436

Authors

Hilal Aydin

Ibrahim Hakan Bucak

Affiliations

Soon will be listed here.

Abstract

Aim: The purpose of this study was to evaluate the relationship between the lunar cycle and attacks observed in patients diagnosed with migraine and under follow-up in our pediatric neurology clinic.

Methods: Cases diagnosed with migraine and under follow-up at the Balıkesir University Medical Faculty Pediatric Neurology Clinic, Turkey, undergoing attacks between 01.09.2019 and 01.09.2021, and whose attacks were recorded were included in the study. Patients' migraine attacks were investigated retrospectively, and the stage of the lunar cycle at which they occurred, based on the lunar calendar, was determined.

Results: The mean age of the patients in the study was 13.39 ± 2.64 (8-17) years. Female gender was observed in the majority of attacks in all lunar cycles, and was most common in the first quarter. Headache was most common in the frontal region during the first quarter and full moon, and auras were also most frequent in the first quarter. Stress and exercise were the most frequent migraine-triggering factors in the first and third quarters, and in the full moon. Migraine attacks were shortest in duration in the full moon, and longest in the first quarter. The frequency of attacks (per week) was highest in the new moon and third quarter, and lowest in the full moon.

Conclusions: This study investigated the relationship between migraine attack characteristics in children and the lunar cycle. It represents the first such investigation of the association between the lunar cycle and pediatric migraine attacks.

Citing Articles

Investigating the potential link between lunar cycle and multiple sclerosis relapses: a call for further studies.

Yousfi N, Mrabet S, Ben Saad H, Chamari K Libyan J Med. 2023; 18(1):2238354.

PMID: 37476952 PMC: 10364568. DOI: 10.1080/19932820.2023.2238354.

References

Bevington M . Lunar biological effects and the magnetosphere. Pathophysiology. 2015; 22(4):211-22. DOI: 10.1016/j.pathophys.2015.08.005. View

Roosli M, Juni P, Braun-Fahrlander C, Brinkhof M, Low N, Egger M . Sleepless night, the moon is bright: longitudinal study of lunar phase and sleep. J Sleep Res. 2006; 15(2):149-53. DOI: 10.1111/j.1365-2869.2006.00520.x. View

Reinberg A, Smolensky M, Touitou Y . The full moon as a synchronizer of circa-monthly biological rhythms: Chronobiologic perspectives based on multidisciplinary naturalistic research. Chronobiol Int. 2016; 33(5):465-79. DOI: 10.3109/07420528.2016.1157083. View

Calver L, Stokes B, Isbister G . The dark side of the moon. Med J Aust. 2009; 191(11-12):692-4. DOI: 10.5694/j.1326-5377.2009.tb03385.x. View

Turanyi C, Ronai K, Zoller R, Veber O, Czira M, Ujszaszi A . Association between lunar phase and sleep characteristics. Sleep Med. 2014; 15(11):1411-6. DOI: 10.1016/j.sleep.2014.06.020. View

Kollerstrom N, Steffert B . Sex difference in response to stress by lunar month: a pilot study of four years' crisis-call frequency. BMC Psychiatry. 2003; 3:20. PMC: 317316. DOI: 10.1186/1471-244X-3-20. View

Bolen R, Campbell Z, Dennis W, Koontz E, Pritchard 3rd P . Effect of lunar phase on frequency of psychogenic nonepileptic events in the EMU. Epilepsy Behav. 2016; 59:62-3. DOI: 10.1016/j.yebeh.2016.03.017. View

Benbadis S, Chang S, Hunter J, Wang W . The influence of the full moon on seizure frequency: myth or reality?. Epilepsy Behav. 2004; 5(4):596-7. DOI: 10.1016/j.yebeh.2004.04.001. View

Belleville G, Foldes-Busque G, Dixon M, Marquis-Pelletier E, Barbeau S, Poitras J . Impact of seasonal and lunar cycles on psychological symptoms in the ED: an empirical investigation of widely spread beliefs. Gen Hosp Psychiatry. 2012; 35(2):192-4. DOI: 10.1016/j.genhosppsych.2012.10.002. View

10.

Benbadis S, Hauser W . An estimate of the prevalence of psychogenic non-epileptic seizures. Seizure. 2000; 9(4):280-1. DOI: 10.1053/seiz.2000.0409. View

11.

Izadyar S, Fahimi G, Hejazi S, Wang D . Effect of meteorological factors and lunar phases on occurrence of psychogenic nonepileptic seizures. Epilepsy Behav. 2021; 121(Pt A):108070. DOI: 10.1016/j.yebeh.2021.108070. View

12.

Owens J, Witmans M . Sleep problems. Curr Probl Pediatr Adolesc Health Care. 2004; 34(4):154-79. DOI: 10.1016/j.cppeds.2003.10.003. View

13.

Carotenuto M, Guidetti V, Ruju F, Galli F, Tagliente F, Pascotto A . Headache disorders as risk factors for sleep disturbances in school aged children. J Headache Pain. 2005; 6(4):268-70. PMC: 3452034. DOI: 10.1007/s10194-005-0204-z. View

14.

Miller V, Palermo T, Powers S, Scher M, HERSHEY A . Migraine headaches and sleep disturbances in children. Headache. 2003; 43(4):362-8. DOI: 10.1046/j.1526-4610.2003.03071.x. View

15.

Cajochen C, Altanay-Ekici S, Munch M, Frey S, Knoblauch V, Wirz-Justice A . Evidence that the lunar cycle influences human sleep. Curr Biol. 2013; 23(15):1485-8. DOI: 10.1016/j.cub.2013.06.029. View

16.

Shechter A, Boivin D . Sleep, Hormones, and Circadian Rhythms throughout the Menstrual Cycle in Healthy Women and Women with Premenstrual Dysphoric Disorder. Int J Endocrinol. 2010; 2010:259345. PMC: 2817387. DOI: 10.1155/2010/259345. View

17.

de Zambotti M, Nicholas C, Colrain I, Trinder J, Baker F . Autonomic regulation across phases of the menstrual cycle and sleep stages in women with premenstrual syndrome and healthy controls. Psychoneuroendocrinology. 2013; 38(11):2618-27. PMC: 3812396. DOI: 10.1016/j.psyneuen.2013.06.005. View

18.

Sjodin A, Hjorth M, Damsgaard C, Ritz C, Astrup A, Michaelsen K . Physical activity, sleep duration and metabolic health in children fluctuate with the lunar cycle: science behind the myth. Clin Obes. 2015; 5(2):60-6. PMC: 4672692. DOI: 10.1111/cob.12092. View

19.

Haba-Rubio J, Marques-Vidal P, Tobback N, Andries D, Preisig M, Kuehner C . Bad sleep? Don't blame the moon! A population-based study. Sleep Med. 2015; 16(11):1321-1326. DOI: 10.1016/j.sleep.2015.08.002. View

20.

Takemura A, Ueda S, Hiyakawa N, Nikaido Y . A direct influence of moonlight intensity on changes in melatonin production by cultured pineal glands of the golden rabbitfish, Siganus guttatus. J Pineal Res. 2006; 40(3):236-41. DOI: 10.1111/j.1600-079X.2005.00306.x. View