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Magnesium for Implants: A Review on the Effect of Alloying Elements on Biocompatibility and Properties

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Publisher MDPI
Date 2022 Aug 26
PMID 36013806
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Abstract

An attempt is made to cover the whole of the topic of biodegradable magnesium (Mg) alloys with a focus on the biocompatibility of the individual alloying elements, as well as shed light on the degradation characteristics, microstructure, and mechanical properties of most binary alloys. Some of the various work processes carried out by researchers to achieve the alloys and their surface modifications have been highlighted. Additionally, a brief look into the literature on magnesium composites as also been included towards the end, to provide a more complete picture of the topic. In most cases, the chronological order of events has not been particularly followed, and instead, this work is concentrated on compiling and presenting an update of the work carried out on the topic of biodegradable magnesium alloys from the recent literature available to us.

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References
1.
Hu Y, Guo X, Qiao Y, Wang X, Lin Q . Preparation of medical Mg-Zn alloys and the effect of different zinc contents on the alloy. J Mater Sci Mater Med. 2022; 33(1):9. PMC: 8727412. DOI: 10.1007/s10856-021-06637-0. View

2.
Pavan C, Delle Piane M, Gullo M, Filippi F, Fubini B, Hoet P . The puzzling issue of silica toxicity: are silanols bridging the gaps between surface states and pathogenicity?. Part Fibre Toxicol. 2019; 16(1):32. PMC: 6697921. DOI: 10.1186/s12989-019-0315-3. View

3.
Li Y, Gao J, Yang L, Shen J, Jiang Q, Wu C . Biodegradable and Bioactive Orthopedic Magnesium Implants with Multilayered Protective Coating. ACS Appl Bio Mater. 2022; 2(8):3290-3299. DOI: 10.1021/acsabm.9b00313. View

4.
Brown A, Zaky S, Ray Jr H, Sfeir C . Porous magnesium/PLGA composite scaffolds for enhanced bone regeneration following tooth extraction. Acta Biomater. 2014; 11:543-53. DOI: 10.1016/j.actbio.2014.09.008. View

5.
Li Y, Wang Y, Shen Z, Miao F, Wang J, Sun Y . A biodegradable magnesium alloy vascular stent structure: Design, optimisation and evaluation. Acta Biomater. 2022; 142:402-412. DOI: 10.1016/j.actbio.2022.01.045. View