» Articles » PMID: 36013375

The Changes in the Severity of Deep Neck Infection Post-UPPP and Tonsillectomy in Patients with OSAS

Overview
Journal Life (Basel)
Specialty Biology
Date 2022 Aug 26
PMID 36013375
Authors
Affiliations
Soon will be listed here.
Abstract

The main aim of this study is to compare the incidence rate and severity of deep neck infection (DNI) in patients post-UPPP+ T (uvulopalatopharyngoplasty plus tonsillectomy) and without UPPP+ T. We utilized the data derived from the Longitudinal Health Insurance Database (LHID) of the National Health Insurance Research Database (NHIRD) in Taiwan from 1 January 2000 to 31 December 2012. Patients who had undergone combined UPPP and tonsillectomy were selected using National Health Insurance (NHI) surgical order. Patients with DNI were selected using International Classification of Diseases (ICD-9-CM) code. A logistic regression model was applied for risk analysis. There were 1574 patients in the UPPP+ T cohort, and 6,296 patients who did not undergo combined UPPP and tonsillectomy for the control group. Our analysis showed that patients with an obstructive sleep apnea syndrome (OSAS) history constitute 76.1% ( = 1198) of the UPPP+ T cohort. Compared to the control group, there was no significantly increased incidence rate of DNI after UPPP+ T within 1-60 months. Patients undergoing combined UPPP and tonsillectomy had a lower intubation rate for DNI, with an adjusted odds ratio of 0.47 (95% CI = 0.32-0.69). The combined UPPP and tonsillectomy does not increase the risk of DNI within 1-60 months. Furthermore, combined UPPP and tonsillectomy can reduce the severity for DNI by decreasing the intubation rate and length of hospitalization.

References
1.
Trevino-Gonzalez J, Maldonado-Chapa F, Gonzalez-Larios A, Morales-Del Angel J, Soto-Galindo G, Zafiro Garcia-Villanueva J . Deep Neck Infections: Demographic and Clinical Factors Associated with Poor Outcomes. ORL J Otorhinolaryngol Relat Spec. 2021; 84(2):130-138. DOI: 10.1159/000517026. View

2.
Wang Y, Wang M, Lin H, Lee K, Chou P . Tonsillectomy and the risk for deep neck infection-a nationwide cohort study. PLoS One. 2015; 10(4):e0117535. PMC: 4388732. DOI: 10.1371/journal.pone.0117535. View

3.
Bitar M, Dowli A, Mourad M . The effect of tonsillectomy on the immune system: A systematic review and meta-analysis. Int J Pediatr Otorhinolaryngol. 2015; 79(8):1184-91. DOI: 10.1016/j.ijporl.2015.05.016. View

4.
Nizam N, Basoglu O, Tasbakan M, Lappin D, Buduneli N . Is there an association between obstructive sleep apnea syndrome and periodontal inflammation?. Clin Oral Investig. 2015; 20(4):659-68. DOI: 10.1007/s00784-015-1544-y. View

5.
Levy P, Pepin J, Arnaud C, Tamisier R, Borel J, Dematteis M . Intermittent hypoxia and sleep-disordered breathing: current concepts and perspectives. Eur Respir J. 2008; 32(4):1082-95. DOI: 10.1183/09031936.00013308. View