High-Purity Fucoxanthin Can Be Efficiently Prepared from by Ethanol-Based Green Method Coupled with Octadecylsilyl (ODS) Column Chromatography

Overview

Journal Mar Drugs

Publisher MDPI

Specialties Biology
Pharmacology

Date 2022 Aug 25

PMID 36005513

Authors

GengJie Zhuang

Yuemei Ye

Junling Zhao

Chengxu Zhou

Junwang Zhu

Yanrong Li

Jinrong Zhang

Xiaojun Yan

Affiliations

Soon will be listed here.

Abstract

The exploitation of new economically valuable microalgae as a sustainable source of minor high-value products can effectively promote the full utilization of microalgae. The efficient preparation of minor products from microalgae remains the challenge, owing to the coexistence of various components with a similar polarity in the microalgae biomass. In this study, a novel approach based on the sustainable-oriented strategy for fucoxanthin (FX) production was proposed, which consisted of four steps, including the culture of microalga, ethanol extraction, ODS column chromatography, and ethanol precipitation. The high-purity FX (around 95%) was efficiently obtained in a total recovery efficiency of 84.28 ± 2.56%. This study reveals that is a potentially promising feedstock for FX production and firstly provides a potentially eco-friendly method for the scale-up preparation of FX from the microalga .

Citing Articles

Efficient Preparation of High-Purity Fucoxanthinol by SpyTag-Tailored Active Cholesterol Esterase Aggregates.

Jin W, Yang T, Chen H, Fang H, Chen W, Xie Q Mar Drugs. 2022; 20(11).

PMID: 36421987 PMC: 9698702. DOI: 10.3390/md20110709.

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