Impact of a Rapid Respiratory Pathogen Panel on Antibiotic and Chest Radiography Usage and Hospital Length of Stay in the Pediatric Inpatient Setting

Overview

Journal Perm J

Specialties General Medicine
Health Services

Date 2022 Aug 24

PMID 36001386

Authors

Lucy Schram

Susan Novak-Weekley

Qiaoling Chen

Paul Han

Affiliations

Soon will be listed here.

Abstract

IntroductionThe objective of this study was to compare the antibiotic initiation rate and duration, hospital length of stay, emergency department (ED) admission rate and chest radiography usage in a pediatric inpatient unit before and after the decentralization of rapid respiratory pathogen panel (RRPP) processing. MethodsThis retrospective cohort study examined antibiotic initiation rates and durations, hospital lengths of stay, ED admission rates, and chest radiography usage from 2 respiratory virus seasons. For the 2014 cohort, RRPPs were processed at a centralized laboratory, and result times averaged 26 hours, whereas for the 2015 cohort, RRPPs were processed on-site with result times averaging 2 hours. Demographic data were collected and demonstrated similar populations. Chi-square testing was used to detect the change of antibiotic initiation rates, ED admission rates, and chest radiography usage after on-site RRPP processing was introduced. Antibiotic duration and hospital length of stay were determined by Wilcoxon rank sum. ResultsThe study population included 94 patients from the 2014 respiratory virus season and 108 patients from the 2015 respiratory virus season. There were no statistically significant differences in gender, ethnicity, or age between the 2 cohorts. Antimicrobial initiation rates during hospital stay decreased from 46% to 27% (p = 0.005). The rate of admission from the ED decreased from 75% to 30% (p < 0.001). There were no statistically significant differences in antibiotic duration, hospital length of stay, or chest radiography usage. ConclusionRapid respiratory pathogen testing is a useful tool that can decrease unnecessary antibiotic initiation and hospital admissions in the pediatric population.

Citing Articles

Multiplex PCR and Antibiotic Use in Children with Community-Acquired Pneumonia.

Del Rosal T, Bote-Gascon P, Falces-Romero I, Sainz T, Baquero-Artigao F, Rodriguez-Molino P Children (Basel). 2024; 11(2).

PMID: 38397359 PMC: 10887858. DOI: 10.3390/children11020245.

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