Present Evidence of Determinants to Predict the Efficacy of Renal Denervation

Overview

Journal Int J Hypertens

Publisher Wiley

Date 2022 Aug 22

PMID 35992203

Authors

Hao Zhou

Yanping Xu

Weijie Chen

Liang Wang

Huaan Du

Hang Liu

Zhiyu Ling

Yuehui Yin

Affiliations

Soon will be listed here.

Abstract

Sympathetic overactivation is one of the main contributors to development and progress of hypertension. Renal denervation (RDN) has been evidenced by series of clinical trials for its efficacy and safety to treat overactivated sympathetic nervous system induced diseases. However, the results were inconsistent and not all patients benefited from RDN. Appropriate patient selection and intraoperative factors to improve the efficacy of RDN need to be solved urgently. Over the decade, research studies on the correlations between indicators and the antihypertensive effects have been conducted and made a fairly well progress. Herein, we comprehensively reviewed the research studies on how to make RDN more predictable or improve the efficacy of RDN and summarized these potential indicators or devices which might be applied in clinical settings.

Citing Articles

Effects of renal denervation on endogenous ouabain in spontaneously hypertensive rats.

Lai X, Wen H, Yang T, Qin F, Zhong X, Pan Y Acta Cir Bras. 2023; 37(11):e371102.

PMID: 36629529 PMC: 9829196. DOI: 10.1590/acb371102.

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