Prevalence, Phytochemical Investigation, and Acaricidal Efficacy Evaluation of , , , and Against Sarcoptic Mange of Camel, Babile District, Ethiopia

Overview

Journal J Parasitol Res

Publisher Wiley

Specialty Parasitology

Date 2022 Aug 22

PMID 35989862

Authors

Sisay Alemu

Yehualashet Bayu

Pawlos Wasihun

Abdallahi Abdurahman

Affiliations

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Abstract

The present study was designed to determine the prevalence of sarcoptic mange from camels; evaluate the presence of secondary metabolites in the methanolic leaf extracts of , , and essential oil; and also evaluate their acaricidal efficacy against camel sarcoptic mange in the Babile District, Ethiopia. Each plant was subjected to qualitative phytochemical screening for the presence or absence of secondary metabolites. The application of each plant extracts was carried out against clinical mange mites with positive and negative controls. Accordingl, a total of 384 camels were examined for the presence of var. The study revealed that an overall prevalence of 67(15.9%) animals was infested by mange mites. The study showed that a higher prevalence was observed in female camel than in male camel with no statistically significant difference ( > 0.05). However, statistically higher prevalence ( < 0.05) was recorded in young camel (28.2%) than adult (10.95%). The study also revealed that statistically higher prevalence ( < 0.05) was observed in poor body conditioned camel (26.3%) than medium (13.5%) and good body condition camels (5.4%). For the evaluation of the efficacy of plant extracts, essential oils and crude extracts of four medicinal plant extracts were diluted at different concentrations from 200 mg/mL to 6.25 mg/mL and added to Petri dishes containing the adult stage of . The efficacy of each plant was determined by comparing the mortality of mites treated with plant extracts with those of mites in nontreated (2% Tween 80) and treated (diazinon) control plates. After 3 h of contact, all concentrations of , , , and showed good acaricidal efficacy compared to controls nontreated control ( < 0.05). After 3 h of exposure to the methanolic extract of and the essential oil of , comparable acaricidal efficacy in causing mites mortality at concentrations of 200 mg/mL has been recorded when compared to reference drugs. The crude extract of showed a lower acaricidal efficacy compared to reference drugs. The present plant extracts studied showed comparable acaricidal efficacy to reference drugs at concentrations of 200 mg/mL. Therefore, further epidemiological and in vivo acaricidal studies as well as toxicity of the plants should be conducted in area to use these plants as alternative treatment option to substitute the use of synthetic drugs for which most of mites developed resistance and control impacts on camel.

Citing Articles

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