» Articles » PMID: 35976308

Normal Pressure Hydrocephalus: an Update

Overview
Publisher Thieme
Specialties Neurology
Psychiatry
Date 2022 Aug 17
PMID 35976308
Authors
Affiliations
Soon will be listed here.
Abstract

Normal pressure hydrocephalus (NPH) has been a topic of debate since its introduction in publications. More frequent in the elderly population, it is characterized by gait disturbance, urinary urge incontinence and cognitive decline. Therefore, it is a clinical-radiological entity with relatively common findings for the age group, which together may have greater specificity. Therefore, its diagnosis must be careful for an adequate selection of patients for treatment with ventricular shunt, since the symptoms are potentially reversible. The tap test has a high positive predictive value as a predictor of therapeutic response, but a negative test does not exclude the possibility of treatment. Scientific efforts in recent years have been directed towards a better understanding of NPH and this narrative review aims to compile recent data from the literature in a didactic way for clinical practice.

Citing Articles

Neurocognitive Safety of Endoscopic Colloid Cyst Resection: Paired Pre- and Post-Operative Cognitive Function from an Exploratory Cohort.

Tosi U, Sacks-Zimmerman A, Villamater F, Spat-Lemus J, Perrine K, Souweidane M Cancers (Basel). 2025; 17(3).

PMID: 39941786 PMC: 11815914. DOI: 10.3390/cancers17030416.


Insights into the Role of the Glymphatic System in the Pathogenesis of Post-hemorrhagic Hydrocephalus.

Massoud A, Noltensmeyer D, Juranek J, Cox Jr C, Velasquez F, Zhu B Mol Neurobiol. 2025; .

PMID: 39821726 DOI: 10.1007/s12035-025-04692-0.


A bibliometric analysis and visualization of normal pressure hydrocephalus.

Chang T, Huang X, Zhang X, Li J, Bai W, Wang J Front Neurol. 2024; 15:1442493.

PMID: 39144708 PMC: 11322097. DOI: 10.3389/fneur.2024.1442493.


Normal-Pressure Hydrocephalus-Like Appearance in Myotonic Dystrophy Type 1.

Suzuki A, Hayashi K, Nakaya Y, Hayashi M, Hayashi K, Kobayashi Y Cureus. 2024; 16(1):e53130.

PMID: 38420055 PMC: 10899733. DOI: 10.7759/cureus.53130.

References
1.
Krauss J, Droste D, Bohus M, Regel J, Scheremet R, Riemann D . The relation of intracranial pressure B-waves to different sleep stages in patients with suspected normal pressure hydrocephalus. Acta Neurochir (Wien). 1995; 136(3-4):195-203. DOI: 10.1007/BF01410626. View

2.
Adams R, Fisher C, Hakim S, Ojemann R, SWEET W . SYMPTOMATIC OCCULT HYDROCEPHALUS WITH "NORMAL" CEREBROSPINAL-FLUID PRESSURE. A TREATABLE SYNDROME. N Engl J Med. 1965; 273:117-26. DOI: 10.1056/NEJM196507152730301. View

3.
Tanaka N, Yamaguchi S, Ishikawa H, Ishii H, Meguro K . Prevalence of possible idiopathic normal-pressure hydrocephalus in Japan: the Osaki-Tajiri project. Neuroepidemiology. 2008; 32(3):171-5. DOI: 10.1159/000186501. View

4.
Bergsneider M, Black P, Klinge P, Marmarou A, Relkin N . Surgical management of idiopathic normal-pressure hydrocephalus. Neurosurgery. 2005; 57(3 Suppl):S29-39. DOI: 10.1227/01.neu.0000168186.45363.4d. View

5.
Cagnin A, Simioni M, Tagliapietra M, Citton V, Pompanin S, Della Puppa A . A Simplified Callosal Angle Measure Best Differentiates Idiopathic-Normal Pressure Hydrocephalus from Neurodegenerative Dementia. J Alzheimers Dis. 2015; 46(4):1033-8. DOI: 10.3233/JAD-150107. View