Surgical Management of Pediatric Salivary Malignant Tumors-A Single-center Cohort Study

Overview

Journal J Surg Oncol

Specialties General Surgery
Oncology

Date 2022 Aug 15

PMID 35969241

Authors

Joseph Lopez

Yu Han Chen

Alana Eagan

Conall Fitzgerald

Robbie Woods

Richard Wong

Jatin Shah

Ian Ganly

Affiliations

Soon will be listed here.

Abstract

Background: The purpose of this study was to report incidence, clinicopathologic behavior, management, and outcome of pediatric patients treated surgically for salivary gland (SG) malignancies.

Methods: Patients who underwent surgery for SG malignancies from 1985 to 2015 were identified. Clinical, pathological, treatment and outcomes data were collected. Disease-specific survival (DSS), recurrence-free survival (RFS), and overall survival (OS) were calculated using Kaplan-Meier method.

Results: Twenty-eight pediatric patients were included. The most common histopathological types were mucoepidermoid (n = 18, 64.3%), acinic cell (n = 7, 25.0%), adenoid cystic (n = 2, 7.1%), and adenocarcinoma (n = 1, 3.6%). Surgical approach varied and ranged from superficial parotidectomy (n = 11, 39.3%) to partial maxillectomy (n = 6, 21.4%). Nine patients (32%) required postoperative radiotherapy. DSS, OS, and RFS probability at 5 years were 96.4%, 96.4%, and 89.3%, respectively.

Conclusion: Pediatric SG malignancies are rare and have favorable outcome at 5 years. Larger, multi-institutional studies are required to better understand the natural history of these rare tumors.

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