Mantle Cell Lymphoma with Aseptic Meningitis Mimicking Hydrocephalus on Brain Imaging
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Abstract
An 83-year-old man underwent head computed tomography (CT) to investigate cognitive decline and gait disturbance and was admitted to undergo a cerebrospinal fluid (CSF) tap test for suspected idiopathic normal-pressure hydrocephalus. He had a history of chemotherapy for mantle cell lymphoma (MCL), but CT on admission showed no evidence of recurrence. After admission, his level of consciousness rapidly deteriorated and CSF examination suggested infiltration of MCL into the central nervous system (CNS). Although CNS involvement in MCL is rare, this case demonstrates that even if recurrence of MCL is not suspected based on CT findings.
References
1.
Marouf F, Glover M, Wininger B, Curry W
. Case 10-2021: A 70-Year-Old Man with Depressed Mood, Unsteady Gait, and Urinary Incontinence. N Engl J Med. 2021; 384(14):1350-1358.
DOI: 10.1056/NEJMcpc2027090.
View
2.
Shah B, Martin P, Sotomayor E
. Mantle cell lymphoma: a clinically heterogeneous disease in need of tailored approaches. Cancer Control. 2012; 19(3):227-35.
PMC: 4015063.
DOI: 10.1177/107327481201900307.
View
3.
Ohmichi T, Kondo M, Itsukage M, Koizumi H, Matsushima S, Kuriyama N
. Usefulness of the convexity apparent hyperperfusion sign in 123I-iodoamphetamine brain perfusion SPECT for the diagnosis of idiopathic normal pressure hydrocephalus. J Neurosurg. 2018; 130(2):398-405.
DOI: 10.3171/2017.9.JNS171100.
View
4.
Maddocks K
. Update on mantle cell lymphoma. Blood. 2018; 132(16):1647-1656.
DOI: 10.1182/blood-2018-03-791392.
View
5.
Cheah C, George A, Gine E, Chiappella A, Kluin-Nelemans H, Jurczak W
. Central nervous system involvement in mantle cell lymphoma: clinical features, prognostic factors and outcomes from the European Mantle Cell Lymphoma Network. Ann Oncol. 2013; 24(8):2119-23.
DOI: 10.1093/annonc/mdt139.
View