» Articles » PMID: 35937729

Cluster Headache Associated with Oculomotor Nerve Palsy: A Case Report and Review of Literature

Overview
Specialty Ophthalmology
Date 2022 Aug 8
PMID 35937729
Authors
Affiliations
Soon will be listed here.
Abstract

Cluster headaches are a series of short, excruciating, and unilateral pain that happens for a short period at a time over days, weeks, or months and may awake people from sleep. It is situated behind, in, or around one eye only with possible radiation to the forehead at the same side. Cluster headache is characterized by many ocular features. However, extraocular muscle involvement is unusual in this type of headache. We present a case of chronic cluster headache associated with diplopia due to oculomotor nerve palsy in a 24-year-old man, which responded successfully to oral steroid. This presentation is rare. Therefore, ophthalmologists and neurologists should consider it in their list of a differential diagnosis. A short course of oral prednisolone has a role in the management of patients in such cases.

References
1.
. Headache Classification Committee of the International Headache Society (IHS) The International Classification of Headache Disorders, 3rd edition. Cephalalgia. 2018; 38(1):1-211. DOI: 10.1177/0333102417738202. View

2.
Figuerola M, Levin G, Leston J, Barontini M . Opioid and sympathetic nervous system activity in cluster headache under verapamil or prednisone treatment. Headache. 1994; 34(5):257-60. DOI: 10.1111/j.1526-4610.1994.hed3405257.x. View

3.
Connors M . Cluster headache: a review. J Am Osteopath Assoc. 1995; 95(9):533-9. View

4.
Neeb L, Anders L, Euskirchen P, Hoffmann J, Israel H, Reuter U . Corticosteroids alter CGRP and melatonin release in cluster headache episodes. Cephalalgia. 2014; 35(4):317-26. DOI: 10.1177/0333102414539057. View

5.
Obermann M, Nagel S, Ose C, Sonuc N, Scherag A, Storch P . Safety and efficacy of prednisone versus placebo in short-term prevention of episodic cluster headache: a multicentre, double-blind, randomised controlled trial. Lancet Neurol. 2020; 20(1):29-37. DOI: 10.1016/S1474-4422(20)30363-X. View