Anti-inflammatory and Immunomodulatory Properties of

Overview

Journal Biomed Res Int

Publisher Wiley

Specialties Biomedical Engineering
Biotechnology
General Medicine

Date 2022 Aug 8

PMID 35937400

Authors

Saeid Vazifeh

Parya Kananpour

Mahna Khalilpour

Sajjad Vazifeh Eisalou

Michael R Hamblin

Affiliations

Soon will be listed here.

Abstract

Background: (garden cress) is a member of the Brassicaceae family that has been utilized for medicinal and culinary purposes in centuries. Anti-inflammatory, antioxidant, immunomodulatory, hepatoprotective, antihypertensive, antiasthmatic, and hypoglycemic properties are found in various portions of the plant. The anti-inflammatory, antioxidant, and immunomodulatory effects of L. sativum were the subject of this review.

Methods: The required information was gathered by searching the Web of Science, PubMed, and Scopus databases for the terms anti-inflammatory, antioxidant, immunomodulatory, immune system, and . Up until February 2022, the search was conducted.

Results: TNF-, IL-6, IL-1, NO, iNOS, and HO-1 levels were reduced, indicating that has anti-inflammatory and immunomodulatory properties. Flavonoids, alkaloids, cyanogenic glycosides, tannins, glucosinolates, sterols, and triterpenes are the key chemical components that contribute to the anti-inflammatory effects. In peritoneal neutrophils, reduced oxidative stress by scavenging free radicals, as evidenced by a drop in superoxide anion and an increase in glutathione.

Conclusion: The anti-inflammatory, antioxidant, and immunomodulatory activities of could be explored in clinical trials to treat inflammatory and immune system illnesses.

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