Antibacterial Activities of Seven Ethnomedicinal Plants from Family

Overview

Journal J Adv Pharm Technol Res

Date 2022 Aug 8

PMID 35935693

Authors

Diannita Harahap

Sarah Niaci

Vivi Mardina

Bintang Zaura

Intan Qanita

Agnia Purnama

Kana Puspita

Diva Rayyan Rizki

Muhammad Iqhrammullah

Affiliations

Soon will be listed here.

Abstract

Serious threat to human health caused by bacterial infection persists as a global concern. It becomes more serious when the burden of multidrug-resistance bacteria is in the increasing trend. To overcome, researches have been conducted to develop antibacterial agents from plant-derived bioactive compounds. This review article focuses on the antibacterial activities of plant extracts from seven members, namely , , , , , , and . First, ethnomedical uses of the aforementioned plants are discussed and followed by the screening results of related phytochemicals. Among many secondary metabolites contained in the extracts of spp., anonaine, nornuciferine, and liriodenine are common and bioactive. The extracts were reported to have bacteriostatic and bactericidal properties against a wide spectrum of bacteria, including multidrug-resistant , , , , , , , , and . We conclude that investigation on the extracts from spp. could contribute to the development of antibacterial agents that could be used against multidrug-resistant bacteria.

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References

Jones K, Patel N, Levy M, Storeygard A, Balk D, Gittleman J . Global trends in emerging infectious diseases. Nature. 2008; 451(7181):990-3. PMC: 5960580. DOI: 10.1038/nature06536. View

Kaczmarek B . Tannic Acid with Antiviral and Antibacterial Activity as A Promising Component of Biomaterials-A Minireview. Materials (Basel). 2020; 13(14). PMC: 7412100. DOI: 10.3390/ma13143224. View

Upadhayay A, Patel G, Pal D, Kumar A . Frequently Used Allopathic and Traditional Medicine for COVID-19 Treatment and Feasibility of Their Integration. Chin J Integr Med. 2022; 28(11):1040-1047. PMC: 9065245. DOI: 10.1007/s11655-021-3512-5. View

Satia Nugraha A, Damayanti Y, Wangchuk P, Keller P . Anti-Infective and Anti-Cancer Properties of the Species: Their Ethnomedicinal Uses, Alkaloid Diversity, and Pharmacological Activities. Molecules. 2019; 24(23). PMC: 6930583. DOI: 10.3390/molecules24234419. View

Purnama A, Mardina V, Puspita K, Qanita I, Rizki D, Hasballah K . Molecular docking of two cytotoxic compounds from leaves against therapeutic molecular target of pancreatic cancer. Narra J. 2024; 1(2):e37. PMC: 10914070. DOI: 10.52225/narraj.v1i2.37. View

Fomogne-Fodjo M, Van Vuuren S, Ndinteh D, Krause R, Olivier D . Antibacterial activities of plants from Central Africa used traditionally by the Bakola pygmies for treating respiratory and tuberculosis-related symptoms. J Ethnopharmacol. 2014; 155(1):123-31. DOI: 10.1016/j.jep.2014.04.032. View

Purnama A, Rizki D, Qanita I, Iqhrammullah M, Ahmad K, Mardina V . Molecular docking investigation of calotropone as a potential natural therapeutic agent against pancreatic cancer. J Adv Pharm Technol Res. 2022; 13(1):44-49. PMC: 8820343. DOI: 10.4103/japtr.japtr_143_21. View

Ciorba V, Odone A, Veronesi L, Pasquarella C, Signorelli C . Antibiotic resistance as a major public health concern: epidemiology and economic impact. Ann Ig. 2015; 27(3):562-79. DOI: 10.7416/ai.2015.2048. View

Wang J, Zhang H, Yan J, Zhang T . Literature review on the distribution characteristics and antimicrobial resistance of bacterial pathogens in neonatal sepsis. J Matern Fetal Neonatal Med. 2020; 35(5):861-870. DOI: 10.1080/14767058.2020.1732342. View

10.

Wink M . Evolution of secondary metabolites from an ecological and molecular phylogenetic perspective. Phytochemistry. 2003; 64(1):3-19. DOI: 10.1016/s0031-9422(03)00300-5. View

11.

De la Cruz-Chacon I, Gonzalez-Esquinca A, Guevara Fefer P, Jimenez Garcia L . Liriodenine, early antimicrobial defence in Annona diversifolia. Z Naturforsch C J Biosci. 2011; 66(7-8):377-84. DOI: 10.1515/znc-2011-7-809. View

12.

Paulo M, Barbosa-Filho J, Lima E, Maia R, Barbosa R, Kaplan M . Antimicrobial activity of benzylisoquinoline alkaloids from Annona salzmanii D.C. J Ethnopharmacol. 1992; 36(1):39-41. DOI: 10.1016/0378-8741(92)90058-y. View

13.

Simeon S, Rios J, Villar A . Antimicrobial activity of Annona cherimolia stem bark alkaloids. Pharmazie. 1990; 45(6):442-3. View

14.

Cahlikova L, Breiterova K, Opletal L . Chemistry and Biological Activity of Alkaloids from the Genus (Amaryllidaceae). Molecules. 2020; 25(20). PMC: 7587589. DOI: 10.3390/molecules25204797. View

15.

Tekwu E, Askun T, Kuete V, Nkengfack A, Nyasse B, Etoa F . Antibacterial activity of selected Cameroonian dietary spices ethno-medically used against strains of Mycobacterium tuberculosis. J Ethnopharmacol. 2012; 142(2):374-82. DOI: 10.1016/j.jep.2012.05.003. View

16.

de la Cruz Chacon I, Gonzalez-Esquinca A . Liriodenine alkaloid in Annona diversifolia during early development. Nat Prod Res. 2011; 26(1):42-9. DOI: 10.1080/14786419.2010.533373. View

17.

Aminimoghadamfarouj N, Nematollahi A, Wiart C . Annonaceae: bio-resource for tomorrow's drug discovery. J Asian Nat Prod Res. 2011; 13(5):465-76. DOI: 10.1080/10286020.2011.570265. View

18.

Al-Nemari R, Al-Senaidy A, Semlali A, Ismael M, Badjah-Hadj-Ahmed A, Ben Bacha A . GC-MS profiling and assessment of antioxidant, antibacterial, and anticancer properties of extracts of Annona squamosa L. leaves. BMC Complement Med Ther. 2020; 20(1):296. PMC: 7541211. DOI: 10.1186/s12906-020-03029-9. View