Potential Ovarian Toxicity and Infertility Risk Following Targeted Anti-cancer Therapies

Overview

Journal Reprod Fertil

Specialty Reproductive Medicine

Date 2022 Aug 5

PMID 35928672

Authors

Roseanne Rosario

Wanyuan Cui

Richard A Anderson

Affiliations

Soon will be listed here.

Abstract

Lay Summary: Compared to traditional chemotherapy agents, anti-cancer therapies are thought to be highly effective at targeting cancer cells but sparing normal cells, resulting in reduced drug side effects. However, many of processes within the cells that these drugs affect are also important for the ovary to work normally, so suppressing them in this way could have long-lasting implications for female fertility. This review examines the potential toxicity of anti-cancer therapies on the ovary.

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