Application Value of Nutrition Support Team in Chemotherapy Period of Colon Cancer Based on Internet Multidisciplinary Treatment Mode

Overview

Journal Comput Math Methods Med

Publisher Hindawi

Specialty Medical Informatics

Date 2022 Aug 2

PMID 35915770

Authors

Jianfeng Chen

Bo Wang

Xiaobin Yin

Qifei Liang

Yucheng Li

Xingjiang Xie

Xuehui Zeng

Affiliations

Soon will be listed here.

Abstract

Objective: To explore the application value of the nutrition support team in chemotherapy period of colon cancer based on the internet multidisciplinary treatment mode.

Methods: For the method of retrospective study, 90 patients with colon cancer admitted to our hospital from August 2018 to August 2020 were selected as the study subjects. They were equally divided into the experimental group ( = 45) and the control group ( = 45) according to the order of initials and the method of parity group. The control group was given conventional nutrition support, and the experimental group was given the nutrition support under the internet multidisciplinary treatment mode. The serum tumor marker levels (CEA and CA19-9), immune function indexes, nutrition indicators, and the incidence of adverse reactions were compared between the two groups before and after intervention.

Results: The serum tumor marker levels in the experimental group after intervention were significantly lower than those in the control group ( < 0.001). The immune function indexes in the experimental group after intervention were significantly better than those in the control group ( < 0.001). The nutrition indicators in the experimental group after intervention were significantly better than those in the control group ( < 0.001). The incidence of gastrointestinal adverse reactions above grade 2 in the experimental group was significantly lower than that in the control group ( < 0.05). There were 20 patients with myelosuppression, 2 patients with neurotoxicity, and 1 patient with hand and foot syndrome in the experimental group, while 22 patients with myelosuppression, 4 patients with neurotoxicity, and 2 patients with hand and foot syndrome in the control group, with no significant difference in the incidence of adverse reactions between the two groups ( > 0.05).

Conclusion: The nutrition support team under the internet multidisciplinary treatment mode can improve the immune function of chemotherapy patients with colon cancer and enhance their nutritional level, thereby reducing the incidence of adverse reactions and improving the chemotherapy effects.

References

Sikavi D, Nguyen L, Haruki K, Ugai T, Ma W, Wang D . The Sulfur Microbial Diet and Risk of Colorectal Cancer by Molecular Subtypes and Intratumoral Microbial Species in Adult Men. Clin Transl Gastroenterol. 2021; 12(8):e00338. PMC: 8323793. DOI: 10.14309/ctg.0000000000000338. View

Wong T, Chen S, Ong S, Shyam S, Kandasami P, Chee W . Study protocol for an open labelled randomised controlled trial of perioperative oral nutrition supplement in breast and colorectal cancer patients undergoing elective surgery. Trials. 2021; 22(1):767. PMC: 8565021. DOI: 10.1186/s13063-021-05716-5. View

Kaska M, Havel E, Javorska L, Matousova K, Paral J, Chobola M . Can early postoperative parenteral nutrition have some impact on postoperative inflammatory response intensity?. Clin Nutr ESPEN. 2021; 45:150-154. DOI: 10.1016/j.clnesp.2021.07.022. View

Yang S, Wang T, Huang C, Chang S, Liang S, Yu C . Influence of albumin and physical activity on postoperative recovery in patients with colorectal cancer: An observational study. Eur J Oncol Nurs. 2021; 54:102027. DOI: 10.1016/j.ejon.2021.102027. View

Gupta A, Gupta E, Hilsden R, Hawel J, Elnahas A, Schlachta C . Preoperative malnutrition in patients with colorectal cancer. Can J Surg. 2021; 64(6):E621-E629. PMC: 8628841. DOI: 10.1503/cjs.016820. View

Humphry N, Wilson T, Cox M, Carter B, Arkesteijn M, Reeves N . Association of Postoperative Clinical Outcomes With Sarcopenia, Frailty, and Nutritional Status in Older Patients With Colorectal Cancer: Protocol for a Prospective Cohort Study. JMIR Res Protoc. 2021; 10(8):e16846. PMC: 8408756. DOI: 10.2196/16846. View

Bhimla A, Mann-Barnes T, Park H, Yeh M, Do P, Aczon F . Effects of Neighborhood Ethnic Density and Psychosocial Factors on Colorectal Cancer Screening Behavior Among Asian American Adults, Greater Philadelphia and New Jersey, United States, 2014-2019. Prev Chronic Dis. 2021; 18:E90. PMC: 8522502. DOI: 10.5888/pcd18.210062. View

Wang W, Chen C, Wang T, Lin K, Liu C . Outcomes of early enteral feeding in patients after curative colorectal cancer surgery: A retrospective comparative study. Eur J Oncol Nurs. 2021; 54:101970. DOI: 10.1016/j.ejon.2021.101970. View

Keskin H, Wang S, Etemadi A, Fan J, Dawsey S, Abnet C . Colorectal cancer in the Linxian China Nutrition Intervention Trial: Risk factors and intervention results. PLoS One. 2021; 16(9):e0255322. PMC: 8443060. DOI: 10.1371/journal.pone.0255322. View

10.

Zohrer P, Hana C, Seyed Khoei N, Molzer C, Hormann-Wallner M, Tosevska A . Gilbert's Syndrome and the Gut Microbiota - Insights From the Case-Control BILIHEALTH Study. Front Cell Infect Microbiol. 2021; 11:701109. PMC: 8481893. DOI: 10.3389/fcimb.2021.701109. View

11.

Sato S, Shiozawa M, Nukada S, Iguchi K, Kazama K, Atsumi Y . Preoperative Pre-albumin Concentration as a Predictor of Short-term Outcomes in Elderly Patients With Colorectal Cancer. Anticancer Res. 2021; 41(10):5195-5202. DOI: 10.21873/anticanres.15338. View

12.

Plassmeier L, Hankir M, Seyfried F . Impact of Excess Body Weight on Postsurgical Complications. Visc Med. 2021; 37(4):287-297. PMC: 8406338. DOI: 10.1159/000517345. View

13.

Macaron C, Mankaney G, Haider M, Mouchli M, Hurley K, Burke C . Chemoprevention Considerations in Patients with Hereditary Colorectal Cancer Syndromes. Gastrointest Endosc Clin N Am. 2021; 32(1):131-146. DOI: 10.1016/j.giec.2021.08.005. View

14.

. World Medical Association Declaration of Helsinki: ethical principles for medical research involving human subjects. JAMA. 2013; 310(20):2191-4. DOI: 10.1001/jama.2013.281053. View

15.

Ramezanzade Tabriz E, Ramezani M, Heydari A, Aledavood S . Health-Promoting Lifestyle in Colorectal Cancer Survivors: A Qualitative Study on the Experiences and Perspectives of Colorectal Cancer Survivors and Healthcare Providers. Asia Pac J Oncol Nurs. 2021; 8(6):696-710. PMC: 8522596. DOI: 10.4103/apjon.apjon-2132. View

16.

Huang L, Liu J, Huang X, Wei C, Mo X, Zhong H . Serum C-Reactive Protein-to-Body Mass Index Ratio Predicts Overall Survival in Patients With Resected Colorectal Cancer. Technol Cancer Res Treat. 2021; 20:15330338211037418. PMC: 8326818. DOI: 10.1177/15330338211037418. View

17.

Koller K, Wilson A, Normolle D, Nicholson J, Li J, Kinross J . Dietary fibre to reduce colon cancer risk in Alaska Native people: the Alaska FIRST randomised clinical trial protocol. BMJ Open. 2021; 11(8):e047162. PMC: 8404459. DOI: 10.1136/bmjopen-2020-047162. View

18.

Petrick J, Barber L, Andersen S, Florio A, Palmer J, Rosenberg L . Racial Disparities and Sex Differences in Early- and Late-Onset Colorectal Cancer Incidence, 2001-2018. Front Oncol. 2021; 11:734998. PMC: 8459723. DOI: 10.3389/fonc.2021.734998. View

19.

Drogan C, Kupfer S . Colorectal Cancer Screening Recommendations and Outcomes in Lynch Syndrome. Gastrointest Endosc Clin N Am. 2021; 32(1):59-74. DOI: 10.1016/j.giec.2021.08.001. View

20.

Murthy S, Antonova L, Dube C, Benchimol E, Le Gal G, Hae R . Multivariable models for advanced colorectal neoplasms in screen-eligible individuals at low-to-moderate risk of colorectal cancer: towards improving colonoscopy prioritization. BMC Gastroenterol. 2021; 21(1):383. PMC: 8524805. DOI: 10.1186/s12876-021-01965-5. View