Brain Prehabilitation for Oncologic Surgery

Overview

Journal Curr Oncol Rep

Publisher Current Science

Specialty Oncology

Date 2022 Jul 28

PMID 35900715

Authors

Neil Daksla

Victoria Nguyen

Zhaosheng Jin

Sergio D Bergese

Affiliations

Soon will be listed here.

Abstract

Purpose Of Review: This review aims to summarize the current research on postoperative cognitive complications, such as delirium and cognitive dysfunction. This includes discussion on preoperative preventive strategies, such as physical and nutritional prehabilitation as well as up-to-date information on neuroprehabilitation.

Recent Findings: Current recommendations for prevention of postoperative delirium have focused on multicomponent interventions. The optimal composition of surgical prehabilitation programs targeting exercise and nutrition has not yet been established. The Neurobics Trial shows that cognitive prehabilitation improves cognitive reserve and may be a useful addition to multimodal surgical prehabilitation. Perioperative management of oncologic patients is often associated with a myriad of challenges, such as the management of tumor-related pathologies, adverse events from neoadjuvant therapy, and chronic metabolic and immunological changes associated with malignancy. In addition, oncologic patients are at increased risk of developing frailty, which adversely affects postoperative recovery and further cancer treatment. As a result, oncologic patients are at considerable risk of developing postoperative cognitive complications, such as delirium and cognitive dysfunction. In this review, we discuss the effect of prehabilitation on postoperative cognitive outcomes.

Citing Articles

Cognitive prehabilitation for older adults undergoing elective surgery: a systematic review and narrative synthesis.

He Y, Wang Z, Zhao Y, Han X, Guo K, Sun N Front Aging Neurosci. 2024; 16:1474504.

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Association of preoperative frailty with risk of postoperative delirium in older patients undergoing craniotomy: a prospective cohort study.

Wei L, Liu M, Zhang S, Chen Y, Wu M, Chen X BMC Surg. 2024; 24(1):272.

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