» Articles » PMID: 35889964

Identification of Three Novel Conidiogenesis-Related Genes in the Nematode-Trapping Fungus

Overview
Journal Pathogens
Date 2022 Jul 27
PMID 35889964
Authors
Affiliations
Soon will be listed here.
Abstract

For filamentous fungi, conidiogenesis is the most common reproductive strategy for environmental dispersal, invasion, and proliferation. Understanding the molecular mechanisms controlling conidiation and increasing conidium yield may provide promising applications in commercial development in the future for nematode-trapping fungi. However, the molecular mechanism for regulating conidium production of filamentous fungi is not fully understood. In this study, we characterized three novel conidiogenesis-related genes via gene knockout in . The absence of the genes and caused significant increases in conidia production, while the absence of resulted in a decrease in conidiogenesis. Moreover, we characterized the ortholog of , a well-known conidiogenesis-related gene in . The deletion of not only completely abolished conidium production but also affected the production of nematode-trapping traps.

Citing Articles

AoRan1 Is Involved in Regulating Conidiation, Stress Resistance, Secondary Metabolism, and Pathogenicity in .

Duan S, Liu Q, Shen Y, Zhu L, Yuan H, Yang J Microorganisms. 2024; 12(9).

PMID: 39338527 PMC: 11434409. DOI: 10.3390/microorganisms12091853.


Characterizing the Role of and in Mycelial and Conidial Development in and Their Role in Secondary Metabolism.

Liu Q, Bai N, Duan S, Shen Y, Zhu L, Yang J Microorganisms. 2024; 12(3).

PMID: 38543666 PMC: 10975216. DOI: 10.3390/microorganisms12030615.


Nematode-induced trap formation regulated by the histone H3K4 methyltransferase AoSET1 in the nematode-trapping fungus Arthrobotrys oligospora.

Miao Q, Wang Z, Yin Z, Liu X, Li R, Zhang K Sci China Life Sci. 2023; 66(11):2663-2679.

PMID: 37233873 DOI: 10.1007/s11427-022-2300-2.

References
1.
Yang J, Wang L, Ji X, Feng Y, Li X, Zou C . Genomic and proteomic analyses of the fungus Arthrobotrys oligospora provide insights into nematode-trap formation. PLoS Pathog. 2011; 7(9):e1002179. PMC: 3164635. DOI: 10.1371/journal.ppat.1002179. View

2.
Noguchi Y, Sano M, Kanamaru K, Ko T, Takeuchi M, Kato M . Genes regulated by AoXlnR, the xylanolytic and cellulolytic transcriptional regulator, in Aspergillus oryzae. Appl Microbiol Biotechnol. 2009; 85(1):141-54. DOI: 10.1007/s00253-009-2236-9. View

3.
Sewall T, Mims C, Timberlake W . Conidium differentiation in Aspergillus nidulans wild-type and wet-white (wetA) mutant strains. Dev Biol. 1990; 138(2):499-508. DOI: 10.1016/0012-1606(90)90215-5. View

4.
Christianson T, Sikorski R, Dante M, Shero J, Hieter P . Multifunctional yeast high-copy-number shuttle vectors. Gene. 1992; 110(1):119-22. DOI: 10.1016/0378-1119(92)90454-w. View

5.
Sermon J, Wevers E, Jansen L, De Spiegeleer P, Vanoirbeek K, Aertsen A . CorA affects tolerance of Escherichia coli and Salmonella enterica serovar Typhimurium to the lactoperoxidase enzyme system but not to other forms of oxidative stress. Appl Environ Microbiol. 2005; 71(11):6515-23. PMC: 1287667. DOI: 10.1128/AEM.71.11.6515-6523.2005. View