Roles of Fungi As a Biocontrol Agent in the Control of Plant Diseases

Overview

Journal Microorganisms

Specialty Microbiology

Date 2022 Jul 27

PMID 35888985

Authors

Wenfeng Weng

Jun Yan

Meiliang Zhou

Xin Yao

Aning Gao

Chao Ma

Jianping Cheng

Jingjun Ruan

Affiliations

Soon will be listed here.

Abstract

fungi (AMF) are a class of beneficial microorganisms that are widely distributed in soil ecosystems and can form symbionts with 80% of terrestrial higher plants, and improve the nutritional status of plants. The use of AMF as a biocontrol method to antagonize soil-borne pathogens has received increasing interest from phytopathologists and ecologists. In this paper, the mechanisms of resistance to diseases induced by AMF and the application of AMF to plant fungal, bacterial, and nematode diseases have been summarized. This study aimed to enhance the potential use of AMF as a biological control method to prevent plant diseases in the future. Root morphological alteration characteristics were explained, including the influence of AMF on root structure, function, and the regulation of AMF via secondary metabolites. AMF can improve the rhizosphere environment by influencing the physical and chemical proprieties of soil, enhancing the growth of other beneficial microorganisms, and by competing with pathogenic microorganisms. Two microorganism types may compete for the same invasive sites in root systems and regulate nutrition distribution. AMF can induce the host plant to form defense systems, including improving phytohormone concentrations, inducing signal substrate production, gene expression regulation, and enhancing protein production.

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References

Guzman A, Montes M, Hutchins L, DeLaCerda G, Yang P, Kakouridis A . Crop diversity enriches arbuscular mycorrhizal fungal communities in an intensive agricultural landscape. New Phytol. 2021; 231(1):447-459. PMC: 9292320. DOI: 10.1111/nph.17306. View

Pozo M, Cordier C, Dumas-Gaudot E, Gianinazzi S, Barea J, Azcon-Aguilar C . Localized versus systemic effect of arbuscular mycorrhizal fungi on defence responses to Phytophthora infection in tomato plants. J Exp Bot. 2002; 53(368):525-34. DOI: 10.1093/jexbot/53.368.525. View

Eke P, Adamou S, Fokom R, Dinango Nya V, Tsouh Fokou P, Wakam L . Arbuscular mycorrhizal fungi alter antifungal potential of lemongrass essential oil against causing root rot in common bean (.). Heliyon. 2020; 6(12):e05737. PMC: 7758371. DOI: 10.1016/j.heliyon.2020.e05737. View

Glazebrook J . Contrasting mechanisms of defense against biotrophic and necrotrophic pathogens. Annu Rev Phytopathol. 2005; 43:205-27. DOI: 10.1146/annurev.phyto.43.040204.135923. View

Li F, Guo Y, Christensen M, Gao P, Li Y, Duan T . An arbuscular mycorrhizal fungus and Epichloë festucae var. lolii reduce Bipolaris sorokiniana disease incidence and improve perennial ryegrass growth. Mycorrhiza. 2017; 28(2):159-169. DOI: 10.1007/s00572-017-0813-9. View

Cai X, Zhao H, Liang C, Li M, Liu R . Effects and Mechanisms of Symbiotic Microbial Combination Agents to Control Tomato Crown and Root Rot Disease. Front Microbiol. 2021; 12:629793. PMC: 8245789. DOI: 10.3389/fmicb.2021.629793. View

Ma X, Li X, Ludewig U . Arbuscular mycorrhizal colonization outcompetes root hairs in maize under low phosphorus availability. Ann Bot. 2020; 127(1):155-166. PMC: 7750718. DOI: 10.1093/aob/mcaa159. View

Vos C, Geerinckx K, Mkandawire R, Panis B, De Waele D, Elsen A . Arbuscular mycorrhizal fungi affect both penetration and further life stage development of root-knot nematodes in tomato. Mycorrhiza. 2011; 22(2):157-63. DOI: 10.1007/s00572-011-0422-y. View

Parvin W, Govender N, Othman R, Jaafar H, Rahman M, Wong M . Phenazine from Pseudomonas aeruginosa UPMP3 induced the host resistance in oil palm (Elaeis guineensis Jacq.)-Ganoderma boninense pathosystem. Sci Rep. 2020; 10(1):15621. PMC: 7518433. DOI: 10.1038/s41598-020-72156-7. View

10.

Elliott A, Daniell T, Cameron D, Field K . A commercial arbuscular mycorrhizal inoculum increases root colonization across wheat cultivars but does not increase assimilation of mycorrhiza-acquired nutrients. Plants People Planet. 2021; 3(5):588-599. PMC: 8607474. DOI: 10.1002/ppp3.10094. View

11.

Chen Q, Wu W, Qi S, Cheng H, Li Q, Ran Q . Arbuscular mycorrhizal fungi improve the growth and disease resistance of the invasive plant Wedelia trilobata. J Appl Microbiol. 2019; 130(2):582-591. DOI: 10.1111/jam.14415. View

12.

Fester T, Hause G . Accumulation of reactive oxygen species in arbuscular mycorrhizal roots. Mycorrhiza. 2005; 15(5):373-9. DOI: 10.1007/s00572-005-0363-4. View

13.

Miransari M, Abrishamchi A, Khoshbakht K, Niknam V . Plant hormones as signals in arbuscular mycorrhizal symbiosis. Crit Rev Biotechnol. 2012; 34(2):123-33. DOI: 10.3109/07388551.2012.731684. View

14.

Balestrini R, Bonfante P . Cell wall remodeling in mycorrhizal symbiosis: a way towards biotrophism. Front Plant Sci. 2014; 5:237. PMC: 4044974. DOI: 10.3389/fpls.2014.00237. View

15.

Bubici G, Kaushal M, Prigigallo M, Gomez-Lama Cabanas C, Mercado-Blanco J . Biological Control Agents Against Fusarium Wilt of Banana. Front Microbiol. 2019; 10:616. PMC: 6459961. DOI: 10.3389/fmicb.2019.00616. View

16.

Steinkellner S, Hage-Ahmed K, Garcia-Garrido J, Illana A, Ocampo J, Vierheilig H . A comparison of wild-type, old and modern tomato cultivars in the interaction with the arbuscular mycorrhizal fungus Glomus mosseae and the tomato pathogen Fusarium oxysporum f. sp. lycopersici. Mycorrhiza. 2011; 22(3):189-94. DOI: 10.1007/s00572-011-0393-z. View

17.

Gao L, Smith F, Smith S . The rmc locus does not affect plant interactions or defence-related gene expression when tomato (Solanum lycopersicum) is infected with the root fungal parasite, Rhizoctonia. Funct Plant Biol. 2020; 33(3):289-296. DOI: 10.1071/FP05153. View

18.

Isayenkov S, Mrosk C, Stenzel I, Strack D, Hause B . Suppression of allene oxide cyclase in hairy roots of Medicago truncatula reduces jasmonate levels and the degree of mycorrhization with Glomus intraradices. Plant Physiol. 2005; 139(3):1401-10. PMC: 1283775. DOI: 10.1104/pp.105.069054. View

19.

Berg G . Plant-microbe interactions promoting plant growth and health: perspectives for controlled use of microorganisms in agriculture. Appl Microbiol Biotechnol. 2009; 84(1):11-8. DOI: 10.1007/s00253-009-2092-7. View

20.

Metwally R, Al-Amri S . Individual and interactive role of Trichoderma viride and arbuscular mycorrhizal fungi on growth and pigment content of onion plants. Lett Appl Microbiol. 2019; 70(2):79-86. DOI: 10.1111/lam.13246. View