Episodic Memory in Amnestic Mild Cognitive Impairment (aMCI) and Alzheimer's Disease Dementia (ADD): Using the "Doors and People" Tool to Differentiate Between Early AMCI-Late AMCI-Mild ADD Diagnostic Groups

Overview

Journal Diagnostics (Basel)

Specialty Radiology

Date 2022 Jul 27

PMID 35885671

Authors

Athanasios Chatzikostopoulos

Despina Moraitou

Magdalini Tsolaki

Elvira Masoura

Georgia Papantoniou

Maria Sofologi

Vasileios Papaliagkas

Georgios Kougioumtzis

Efthymios Papatzikis

Affiliations

Soon will be listed here.

Abstract

Episodic memory is the type of memory that allows the recollection of personal experiences containing information on what has happened and, also, where and when it happened. Because of its sensitivity to neurodegenerative diseases and the aging of the brain, it is considered a hallmark of Alzheimer's disease dementia (ADD). The objective of the present study was to examine episodic memory in amnestic mild cognitive impairment (aMCI) and ADD. Patients with the diagnosis of early aMCI, late aMCI, and mild ADD were evaluated using the Doors and People tool which consists of four subtests examining different aspects of episodic memory. The statistical analysis with receiver operating characteristic curves (ROC) showed the discriminant potential and the cutoffs of every subtest. Overall, the evaluation of episodic memory with the Doors and People tool can discriminate with great sensitivity between the different groups of people with AD and, especially, early aMCI, late aMCI, and mild ADD patients.

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