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Medical Management After Lancehead Snakebite in North Amazon: A Case Report of Long-Term Disability

Overview
Journal Toxins (Basel)
Publisher MDPI
Specialty Toxicology
Date 2022 Jul 25
PMID 35878232
Authors
Affiliations
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Abstract

Snakebites are a major public health problem in indigenous communities in Brazil, leading to acute local and systemic damage with resulting deficiencies. Long-term musculoskeletal disabilities related to snakebites have been a neglected area of research. (lancehead) snakes are responsible for most of the permanent sequelae related to snakebites in Latin America. Here, we present a case report of a 32-year-old male indigenous patient who was envenomed by a species. The patient was clinically followed for a period of approximately 2 years and 6 months, during which time he experienced a loss of musculoskeletal tissue and required several medical procedures such as debridement, tissue reconstruction, and physical therapy, which resulted in a recovery of mobility, though with a permanent sequelae in gait. This case report shows how snakebites have a significant impact on health systems, as victims require physiotherapy, plastic surgery, and orthopedics services, as well as social support for reintegration into their local communities.

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References
1.
Sousa J, de Oliveira S, Sachett J, Fan H, Monteiro W . Low accuracy of microscopic hematuria in detecting coagulopathy from pit viper bites, Brazilian Amazon. Clin Toxicol (Phila). 2019; 57(9):816-818. DOI: 10.1080/15563650.2018.1560463. View

2.
Wen F, Monteiro W, Moura da Silva A, Tambourgi D, da Silva I, Sampaio V . Snakebites and scorpion stings in the Brazilian Amazon: identifying research priorities for a largely neglected problem. PLoS Negl Trop Dis. 2015; 9(5):e0003701. PMC: 4440781. DOI: 10.1371/journal.pntd.0003701. View

3.
Otero-Patino R . Epidemiological, clinical and therapeutic aspects of Bothrops asper bites. Toxicon. 2009; 54(7):998-1011. DOI: 10.1016/j.toxicon.2009.07.001. View

4.
Sajevic T, Leonardi A, Krizaj I . Haemostatically active proteins in snake venoms. Toxicon. 2011; 57(5):627-45. DOI: 10.1016/j.toxicon.2011.01.006. View

5.
Oliveira S, C Alves E, S Santos A, T Pereira J, S Sarraff L, Nascimento E . Factors Associated with Systemic Bleeding in Envenomation in a Tertiary Hospital in the Brazilian Amazon. Toxins (Basel). 2019; 11(1). PMC: 6356762. DOI: 10.3390/toxins11010022. View