Metabolic Resistance in Abamectin-Resistant Mediterranean from Northern China

Overview

Journal Toxins (Basel)

Publisher MDPI

Specialty Toxicology

Date 2022 Jul 25

PMID 35878162

Authors

Ran Wang

Yong Fang

Wunan Che

Qinghe Zhang

Jinda Wang

Chen Luo

Affiliations

Soon will be listed here.

Abstract

Abamectin, produced by the soil-dwelling actinomycete , belongs to the macrocyclic lactones class of pesticides, has nematocidal, acaricidal, and insecticidal activity, and is highly effective when used against targeted species. , the tobacco whitefly, is a highly destructive insect to agricultural production worldwide, and various insecticide-resistant strains have been identified in China. Here, we monitored levels of resistance to abamectin in twelve field-collected populations from northern China, and confirmed that, compared with the lab reference strain, six field populations exhibited strong abamectin resistance, while the other six exhibited low-to-medium resistance. Among these, the Xinzheng (XZ) population displayed about a 40-fold increased resistance to abamectin, and experienced significant cross-resistance to chlorpyrifos and imidacloprid. The abamectin resistance of XZ was found to be autosomal and incompletely dominant. Metabolic enzyme and synergism tests were conducted, and two metabolic enzymes, glutathione S-transferase and P450 monooxygenase, were found to be conducive to the field-developed abamectin resistance of the XZ population. The above results provide valuable information that can be used in identifying new pest control strategies and delaying the evolution of resistance to abamectin in field populations of whiteflies.

Citing Articles

Transcriptome Analysis Unveils Molecular Mechanisms of Acaricide Resistance in Two-Spotted Spider Mite Populations on Hops.

Koirala B K S, Bhattarai G, Adesanya A, Moural T, Lavine L, Walsh D Int J Mol Sci. 2025; 25(24.

PMID: 39769060 PMC: 11678639. DOI: 10.3390/ijms252413298.

QTL mapping provides new insights into emamectin benzoate resistance in salmon lice, Lepeophtheirus salmonis.

Sturm A, Carmona-Antonanzas G, Humble J, Croton C, Boyd S, Mphuti R BMC Genomics. 2024; 25(1):1212.

PMID: 39695954 PMC: 11657612. DOI: 10.1186/s12864-024-11096-2.

Omics approaches to unravel insecticide resistance mechanism in (Gennadius) (Hemiptera: Aleyrodidae).

Rosli M, Syed Jaafar S, Azizan K, Yaakop S, Aizat W PeerJ. 2024; 12:e17843.

PMID: 39247549 PMC: 11380842. DOI: 10.7717/peerj.17843.

Effect of High Temperature on Abamectin and Thiamethoxam Tolerance in MEAM1 (Hemiptera: Aleyrodidae).

Zhou M, Liu Y, Wang Y, Chang Y, Wu Q, Gong W Insects. 2024; 15(6).

PMID: 38921114 PMC: 11203426. DOI: 10.3390/insects15060399.

Insecticide Resistance and Its Management in Two Invasive Cryptic Species of in China.

Wang Q, Luo C, Wang R Int J Mol Sci. 2023; 24(7).

PMID: 37047017 PMC: 10094485. DOI: 10.3390/ijms24076048.

References

Pan H, Chu D, Ge D, Wang S, Wu Q, Xie W . Further spread of and domination by Bemisia tabaci (Hemiptera: Aleyrodidae) biotype Q on field crops in China. J Econ Entomol. 2011; 104(3):978-85. DOI: 10.1603/ec11009. View

Bradford M . A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976; 72:248-54. DOI: 10.1016/0003-2697(76)90527-3. View

Enayati A, Ranson H, Hemingway J . Insect glutathione transferases and insecticide resistance. Insect Mol Biol. 2005; 14(1):3-8. DOI: 10.1111/j.1365-2583.2004.00529.x. View

Wang S, Zhang Y, Yang X, Xie W, Wu Q . Resistance Monitoring for Eight Insecticides on the Sweetpotato Whitefly (Hemiptera: Aleyrodidae) in China. J Econ Entomol. 2017; 110(2):660-666. DOI: 10.1093/jee/tox040. View

De Barro P, Liu S, Boykin L, Dinsdale A . Bemisia tabaci: a statement of species status. Annu Rev Entomol. 2010; 56:1-19. DOI: 10.1146/annurev-ento-112408-085504. View

Hogenhout S, Ammar E, Whitfield A, Redinbaugh M . Insect vector interactions with persistently transmitted viruses. Annu Rev Phytopathol. 2008; 46:327-59. DOI: 10.1146/annurev.phyto.022508.092135. View

Wei Q, Lei Z, Nauen R, Cai D, Gao Y . Abamectin resistance in strains of vegetable leafminer, Liriomyza sativae (Diptera: Agromyzidae) is linked to elevated glutathione S-transferase activity. Insect Sci. 2015; 22(2):243-50. DOI: 10.1111/1744-7917.12080. View

Bielza P, Quinto V, Fernandez E, Gravalos C, Abellan J, Cifuentes D . Inheritance of resistance to acrinathrin in Frankliniella occidentalis (Thysanoptera: Thripidae). Pest Manag Sci. 2008; 64(5):584-8. DOI: 10.1002/ps.1540. View

Pavlidi N, Vontas J, Van Leeuwen T . The role of glutathione S-transferases (GSTs) in insecticide resistance in crop pests and disease vectors. Curr Opin Insect Sci. 2018; 27:97-102. DOI: 10.1016/j.cois.2018.04.007. View

10.

Campbell W . History of avermectin and ivermectin, with notes on the history of other macrocyclic lactone antiparasitic agents. Curr Pharm Biotechnol. 2011; 13(6):853-65. DOI: 10.2174/138920112800399095. View

11.

Clark J, Scott J, Campos F, Bloomquist J . Resistance to avermectins: extent, mechanisms, and management implications. Annu Rev Entomol. 1995; 40:1-30. DOI: 10.1146/annurev.en.40.010195.000245. View

12.

Meng X, Wu Z, Jiang C, Guan D, Zhang N, Jiang H . Identification and characterization of glutathione S-transferases and their potential roles in detoxification of abamectin in the rice stem borer, Chilo suppressalis. Pestic Biochem Physiol. 2022; 182:105050. DOI: 10.1016/j.pestbp.2022.105050. View

13.

Wang Z, Yan H, Yang Y, Wu Y . Biotype and insecticide resistance status of the whitefly Bemisia tabaci from China. Pest Manag Sci. 2010; 66(12):1360-6. DOI: 10.1002/ps.2023. View

14.

Wang F, Liu J, Chen P, Li H, Ma J, Liu Y . Bemisia tabaci (Hemiptera: Aleyrodidae) Insecticide Resistance in Shandong Province, China. J Econ Entomol. 2019; 113(2):911-917. DOI: 10.1093/jee/toz315. View

15.

Xu D, He Y, Zhang Y, Xie W, Wu Q, Wang S . Status of pesticide resistance and associated mutations in the two-spotted spider mite, Tetranychus urticae, in China. Pestic Biochem Physiol. 2018; 150:89-96. DOI: 10.1016/j.pestbp.2018.07.008. View

16.

Pan H, Preisser E, Chu D, Wang S, Wu Q, Carriere Y . Insecticides promote viral outbreaks by altering herbivore competition. Ecol Appl. 2015; 25(6):1585-95. DOI: 10.1890/14-0752.1. View

17.

STONE B . A formula for determining degree of dominance in cases of monofactorial inheritance of resistance to chemicals. Bull World Health Organ. 1968; 38(2):325-6. PMC: 2554319. View

18.

Pu X, Yang Y, Wu S, Wu Y . Characterisation of abamectin resistance in a field-evolved multiresistant population of Plutella xylostella. Pest Manag Sci. 2009; 66(4):371-8. DOI: 10.1002/ps.1885. View

19.

Wang Z, Yao M, Wu Y . Cross-resistance, inheritance and biochemical mechanisms of imidacloprid resistance in B-biotype Bemisia tabaci. Pest Manag Sci. 2009; 65(11):1189-94. DOI: 10.1002/ps.1808. View

20.

Liao C, Xia W, Feng Y, Li G, Liu H, Dou W . Characterization and functional analysis of a novel glutathione S-transferase gene potentially associated with the abamectin resistance in Panonychus citri (McGregor). Pestic Biochem Physiol. 2016; 132:72-80. DOI: 10.1016/j.pestbp.2015.11.002. View