Acute Trimethyltin Limbic-cerebellar Syndrome

Overview

Journal Neurology

Specialty Neurology

Date 1987 Jun 1

PMID 3587645

Citations 26

Authors

R BESSER

G Kramer

R Thumler

J Bohl

L Gutmann

H C Hopf

Affiliations

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Abstract

An acute limbic-cerebellar syndrome was seen in six industrial workers who inhaled trimethyltin (TMT). Clinical features included hearing loss, disorientation, confabulation, amnesia, aggressiveness, hyperphagia, disturbed sexual behavior, complex partial and tonic-clonic seizures, nystagmus, ataxia, and mild sensory neuropathy. Severity paralleled maximal urinary organotin levels. One patient died and two remained seriously disabled.

Citing Articles

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Effect of rottlerin on astrocyte phenotype polarization after trimethyltin insult in the dentate gyrus of mice.

Hwang Y, Kim H, Shin E J Neuroinflammation. 2022; 19(1):142.

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Neuroprotective Effect of ' Water Extract on Trimethyltin-Induced Seizures and Hippocampal Neurodegeneration.

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Autophagy in trimethyltin-induced neurodegeneration.

Pompili E, Fabrizi C, Fumagalli L, Fornai F J Neural Transm (Vienna). 2020; 127(7):987-998.

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