Associations Between Combined Exposure to Environmental Hazards and Social Stressors at the Neighborhood Level and Individual Perinatal Outcomes in the ECHO-wide Cohort

Overview

Journal Health Place

Publisher Elsevier

Specialty Public Health

Date 2022 Jul 25

PMID 35872389

Authors

Sheena E Martenies

Mingyu Zhang

Anne E Corrigan

Anton Kvit

Timothy Shields

William Wheaton

Theresa M Bastain

Carrie V Breton

Dana Dabelea

Rima Habre

Sheryl Magzamen

Amy M Padula

Deana Around Him

Carlos A Camargo Jr

Whitney Cowell

Lisa A Croen

Sean Deoni

Todd M Everson

Tina V Hartert

Alison E Hipwell

Cindy T McEvoy

Rachel Morello-Frosch

Thomas G OConnor

Michael Petriello

Sheela Sathyanarayana

Joseph B Stanford

Tracey J Woodruff

Rosalind J Wright

Amii M Kress

Affiliations

Soon will be listed here.

Abstract

Limited studies examine how prenatal environmental and social exposures jointly impact perinatal health. Here we investigated relationships between a neighborhood-level combined exposure (CE) index assessed during pregnancy and perinatal outcomes, including birthweight, gestational age, and preterm birth. Across all participants, higher CE index scores were associated with small decreases in birthweight and gestational age. We also observed effect modification by race; infants born to Black pregnant people had a greater risk of preterm birth for higher CE values compared to White infants. Overall, our results suggest that neighborhood social and environmental exposures have a small but measurable joint effect on neonatal indicators of health.

Citing Articles

High-Risk Infant Developmental Outcome Is Associated with Medical Complexity and Neighborhood Opportunity.

Yeo E, Young N, Cleveland 3rd J, Simon T, Vanderbilt D, Espinoza J J Pediatr. 2024; 279:114433.

PMID: 39672373 PMC: 11903178. DOI: 10.1016/j.jpeds.2024.114433.

Advancing Understanding of Chemical Exposures and Maternal-child Health Through the U.S. Environmental Influences on Child Health Outcomes (ECHO) Program: A Scoping Review.

Barrett E, Ames J, Eick S, Peterson A, Rivera-Nunez Z, Starling A Curr Environ Health Rep. 2024; 11(3):390-403.

PMID: 38985433 PMC: 11324705. DOI: 10.1007/s40572-024-00456-5.

How the Environmental Influences on Child Health Outcome (ECHO) cohort can spur discoveries in environmental epidemiology.

Park C, Blaisdell C, Arteaga S, Mash C, Laessig S, Hanspal M Am J Epidemiol. 2024; 193(9):1219-1223.

PMID: 38760171 PMC: 11369221. DOI: 10.1093/aje/kwae073.

Cumulative Exposures to Environmental and Socioeconomic Risk Factors in Milwaukee County, Wisconsin.

Kodros J, Carter E, Oke O, Wilson A, Jathar S, Magzamen S Geohealth. 2024; 8(5):e2023GH000927.

PMID: 38711844 PMC: 11072195. DOI: 10.1029/2023GH000927.

Neighborhood deprivation in relation to ovarian reserve and outcomes of ovarian stimulation among oocyte donors.

Suresh T, LaPointe S, Lee J, Nagy Z, Shapiro D, Kramer M Fertil Steril. 2024; 122(2):316-325.

PMID: 38461907 PMC: 11283953. DOI: 10.1016/j.fertnstert.2024.03.002.

References

Bobb J, Valeri L, Claus Henn B, Christiani D, Wright R, Mazumdar M . Bayesian kernel machine regression for estimating the health effects of multi-pollutant mixtures. Biostatistics. 2014; 16(3):493-508. PMC: 5963470. DOI: 10.1093/biostatistics/kxu058. View

Rakers F, Rupprecht S, Dreiling M, Bergmeier C, Witte O, Schwab M . Transfer of maternal psychosocial stress to the fetus. Neurosci Biobehav Rev. 2017; . DOI: 10.1016/j.neubiorev.2017.02.019. View

Savitz D, Bobb J, Carr J, Clougherty J, Dominici F, Elston B . Ambient fine particulate matter, nitrogen dioxide, and term birth weight in New York, New York. Am J Epidemiol. 2013; 179(4):457-66. PMC: 3908629. DOI: 10.1093/aje/kwt268. View

Kothari C, Paul R, Dormitorio B, Ospina F, James A, Lenz D . The interplay of race, socioeconomic status and neighborhood residence upon birth outcomes in a high black infant mortality community. SSM Popul Health. 2018; 2:859-867. PMC: 5757914. DOI: 10.1016/j.ssmph.2016.09.011. View

Ponce N, Hoggatt K, Wilhelm M, Ritz B . Preterm birth: the interaction of traffic-related air pollution with economic hardship in Los Angeles neighborhoods. Am J Epidemiol. 2005; 162(2):140-8. PMC: 3636775. DOI: 10.1093/aje/kwi173. View

Peterman N, Kaptur B, Lewis M, Ades L, Carpenter K . Prematurity and low birth weight: geospatial analysis and recent trends. Matern Health Neonatol Perinatol. 2022; 8(1):2. PMC: 9052599. DOI: 10.1186/s40748-022-00137-x. View

Padula A, Mortimer K, Tager I, Hammond S, Lurmann F, Yang W . Traffic-related air pollution and risk of preterm birth in the San Joaquin Valley of California. Ann Epidemiol. 2014; 24(12):888-95e4. PMC: 4355392. DOI: 10.1016/j.annepidem.2014.10.004. View

Shmool J, Bobb J, Ito K, Elston B, Savitz D, Ross Z . Area-level socioeconomic deprivation, nitrogen dioxide exposure, and term birth weight in New York City. Environ Res. 2015; 142:624-32. PMC: 4715366. DOI: 10.1016/j.envres.2015.08.019. View

Givens M, Teal E, Patel V, Manuck T . Preterm birth among pregnant women living in areas with high social vulnerability. Am J Obstet Gynecol MFM. 2021; 3(5):100414. PMC: 8555707. DOI: 10.1016/j.ajogmf.2021.100414. View

10.

Savchev S, Sanz-Cortes M, Cruz-Martinez R, Arranz A, Botet F, Gratacos E . Neurodevelopmental outcome of full-term small-for-gestational-age infants with normal placental function. Ultrasound Obstet Gynecol. 2013; 42(2):201-6. DOI: 10.1002/uog.12391. View

11.

Payne-Sturges D, Gee G, Cory-Slechta D . Confronting Racism in Environmental Health Sciences: Moving the Science Forward for Eliminating Racial Inequities. Environ Health Perspect. 2021; 129(5):55002. PMC: 8096378. DOI: 10.1289/EHP8186. View

12.

Wing J, Sanchez B, Adar S, Meurer W, Morgenstern L, Smith M . Synergism of Short-Term Air Pollution Exposures and Neighborhood Disadvantage on Initial Stroke Severity. Stroke. 2017; 48(11):3126-3129. PMC: 5679432. DOI: 10.1161/STROKEAHA.117.018816. View

13.

van Wassenaer A . Neurodevelopmental consequences of being born SGA. Pediatr Endocrinol Rev. 2006; 2(3):372-7. View

14.

Blumenshine P, Egerter S, Barclay C, Cubbin C, Braveman P . Socioeconomic disparities in adverse birth outcomes: a systematic review. Am J Prev Med. 2010; 39(3):263-72. DOI: 10.1016/j.amepre.2010.05.012. View

15.

Grobman W, Parker C, Willinger M, Wing D, Silver R, Wapner R . Racial Disparities in Adverse Pregnancy Outcomes and Psychosocial Stress. Obstet Gynecol. 2018; 131(2):328-335. PMC: 5785441. DOI: 10.1097/AOG.0000000000002441. View

16.

Dongarwar D, Tahseen D, Wang L, Aliyu M, Salihu H . Trends and predictors of preterm birth among Asian Americans by ethnicity, 1992-2018. J Matern Fetal Neonatal Med. 2021; 35(25):5881-5887. DOI: 10.1080/14767058.2021.1900103. View

17.

Martenies S, Allshouse W, Starling A, Ringham B, Glueck D, Adgate J . Combined environmental and social exposures during pregnancy and associations with neonatal size and body composition: the Healthy Start study. Environ Epidemiol. 2019; 3(2). PMC: 6775643. DOI: 10.1097/EE9.0000000000000043. View

18.

Douthit N, Kiv S, Dwolatzky T, Biswas S . Exposing some important barriers to health care access in the rural USA. Public Health. 2015; 129(6):611-20. DOI: 10.1016/j.puhe.2015.04.001. View

19.

Gillman M, Blaisdell C . Environmental influences on Child Health Outcomes, a Research Program of the National Institutes of Health. Curr Opin Pediatr. 2018; 30(2):260-262. PMC: 6020137. DOI: 10.1097/MOP.0000000000000600. View

20.

Heo S, Fong K, Bell M . Risk of particulate matter on birth outcomes in relation to maternal socio-economic factors: a systematic review. Environ Res Lett. 2021; 14(12). PMC: 8186490. DOI: 10.1088/1748-9326/ab4cd0. View