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Lighting the Way to Host-directed Immunotherapeutics

Overview
Journal Cell Chem Biol
Publisher Cell Press
Specialty Biochemistry
Date 2022 Jul 22
PMID 35868235
Authors
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Abstract

Developing broad-spectrum, host-directed antiviral therapeutics can be adapted to combat emerging viruses. In this issue of Cell Chemical Biology, Maarifi and colleagues implement a Nano luciferase reporter-based protein complementation assay to screen for small molecules and identify Gilteritinib, which enhances interferon induction and antagonizes virus replication.

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