» Articles » PMID: 35863707

Particle Surface Area, Ultrafine Particle Number Concentration, and Cardiovascular Hospitalizations

Overview
Journal Environ Pollut
Date 2022 Jul 21
PMID 35863707
Authors
Affiliations
Soon will be listed here.
Abstract

While the health impacts of larger particulate matter, such as PM and PM, have been studied extensively, research regarding ultrafine particles (UFPs or PM) and particle surface area concentration (PSC) is lacking. This case-crossover study assessed the associations between exposure to PSC and UFP number concentration (UFPnc) and hospital admissions for cardiovascular diseases (CVDs) in New York State (NYS), 2013-2018. We used a time-stratified case-crossover design to compare the PSC and UFPnc levels between hospitalization days and control days (similar days without admissions) for each CVD case. We utilized NYS hospital discharge data to identify all CVD cases who resided in NYS. UFP simulation data from GEOS-Chem-APM, a state-of-the-art chemical transport model, was used to define PSC and UFPnc. Using a multi-pollutant model and conditional logistic regression, we assessed excess risk (ER)% per inter-quartile change of PSC and UFPnc after controlling for meteorological factors, co-pollutants, and time-varying variables. We found immediate and lasting associations between PSC and overall CVDs (lag0-lag0-6: ERs% (95% CI%) ranges: 0.4 (0.1,0.7) - 0.9 (0.7-1.2), and delayed and prolonged ERs%: 0.1-0.3 (95% CIs: 0.1-0.5) between UFPnc and CVDs (lag0-3-lag0-6). Exposure to larger PSC was associated with immediate ER increases in stroke, hypertension, and ischemic heart diseases (1.1%, 0.7%, 0.8%, respectively, all p < 0.05). The adverse effects of PSC on CVDs were highest among children (5-17 years old), in the fall and winter, and during cold temperatures. In conclusion, we found an immediate, lasting effects of PSC on overall CVDs and a delayed, prolonged impact of UFPnc. PSC was a more sensitive indicator than UFPnc. The PSC effects were higher among certain CVD subtypes, in children, in certain seasons, and during cold days. Further studies are needed to validate our findings and evaluate the long-term effects.

Citing Articles

Characteristics of airborne particles emitted from typical indoor combustion sources.

Geng C, Wu X, Wang T, Fu H Front Public Health. 2025; 13:1540166.

PMID: 40046112 PMC: 11880257. DOI: 10.3389/fpubh.2025.1540166.


Association between Ambient Ultrafine Particles and Neurodevelopmental Delay in Preschoolers in Shanghai, China.

Rong M, Shen Y, Ge Y, Du W, Kan H, Cai J Environ Health (Wash). 2025; 3(1):102-110.

PMID: 39839251 PMC: 11744390. DOI: 10.1021/envhealth.4c00102.


Spatiotemporal Mapping of Ultrafine Particle Fluxes in an Office HVAC System with a Diffusion Charger Sensor Array.

Wagner D, Jung N, Boor B ACS EST Air. 2025; 2(1):49-63.

PMID: 39817256 PMC: 11730965. DOI: 10.1021/acsestair.4c00140.


Size-segregated content of heavy metals and polycyclic aromatic hydrocarbons in airborne particles emitted by indoor sources.

Caracci E, Iannone A, Carriera F, Notardonato I, Pili S, Murru A Sci Rep. 2024; 14(1):20739.

PMID: 39237605 PMC: 11377746. DOI: 10.1038/s41598-024-70978-3.


The Joint Effects of Thunderstorms and Power Outages on Respiratory-Related Emergency Visits and Modifying and Mediating Factors of This Relationship.

Lin S, Qi Q, Liu H, Deng X, Trees I, Yuan X Environ Health Perspect. 2024; 132(6):67002.

PMID: 38829734 PMC: 11166412. DOI: 10.1289/EHP13237.