Screening for Subclinical Interstitial Lung Disease in Rheumatoid Arthritis Patients: Functional and Radiological Methods

Overview

Journal Turk Thorac J

Publisher Aves

Specialty Pulmonary Medicine

Date 2022 Jul 18

PMID 35848433

Authors

Heba Wagih Abdelwahab

Nesrein M Shalabi

Mahitab Mohamed Rashad Ghoneim

Nesrine Saad Farrag

Fatma Hamdy

Fatma Elhoseiny

Raed Elmetwally Ali

Affiliations

Soon will be listed here.

Abstract

Objective: Interstitial lung disease is the most frequent lung symptom of rheumatoid arthritis and is a significant contributor to morbid- ity. As a result, the target of this research was to measure the frequency of radiological and functional abnormalities in rheumatoid arthritis patients who did not have any respiratory symptoms.

Material And Methods: This study consists of 30 patients diagnosed with rheumatoid arthritis. All involved cases were exposed to entire history taking and clinical examination. All patients were examined by high-resolution computed tomography and pulmonary function tests.

Results: According to the computed tomography visual score, 73.3% showed interstitial lung disease. The most common abnormalities were reticular patterns (46.7%) followed by nodular patterns (40%) and septal lines (23.3%). However, 36% of the patients had a normal pulmonary function, while 32% had a small airway affection, 20% had restrictive lung disease, and 12% had obstructive lung disease. A significant association was found between supine expiratory volume and computed tomography visual score. Results showed no associa- tion between interstitial lung disease and all lung function test parameters.

Conclusion: Subclinical interstitial lung disease is frequent among rheumatoid arthritis patents. A combination of pulmonary func- tion tests with computed tomography is essential to enhance the recognition of subclinical interstitial lung disease as normal pulmonary function alone cannot exclude its presence.

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