» Articles » PMID: 35846336

Integrated Digital Health Solutions in the Management of Growth Disorders in Pediatric Patients Receiving Growth Hormone Therapy: A Retrospective Analysis

Overview
Specialty Endocrinology
Date 2022 Jul 18
PMID 35846336
Authors
Affiliations
Soon will be listed here.
Abstract

Digital health has seen rapid advancements over the last few years in helping patients and their healthcare professionals better manage treatment for a variety of illnesses, including growth hormone (GH) therapy for growth disorders in children and adolescents. For children and adolescents requiring such therapy, as well as for their parents, the treatment is longitudinal and often involves daily injections plus close progress monitoring; a sometimes daunting task when young children are involved. Here, we describe our experience in offering devices and digital health tools to support GH therapy across some 40 countries. We also discuss how this ecosystem of care has evolved over the years based on learnings and advances in technology. Finally, we offer a glimpse of future planned enhancements and directions for digital health to play a bigger role in better managing conditions treated with GH therapy, as well as model development for adherence prediction. The continued aim of these technologies is to improve clinical decision making and support for GH-treated patients, leading to better outcomes.

Citing Articles

Telemedicine Integrated Care Versus In-Person Care Mode for Patients With Short Stature: Comprehensive Comparison of a Retrospective Cohort Study.

Wang Y, Zhang P, Xing Y, Shi H, Cui Y, Wei Y J Med Internet Res. 2024; 26:e57814.

PMID: 39560983 PMC: 11615543. DOI: 10.2196/57814.


Opportunities for digitally-enabled personalization and decision support for pediatric growth hormone therapy.

Dimitri P, van Dommelen P, Banerjee I, Bellazzi R, Ciaccio M, De Arriba Munoz A Front Endocrinol (Lausanne). 2024; 15:1436778.

PMID: 39473505 PMC: 11518754. DOI: 10.3389/fendo.2024.1436778.


Use of connected injection device has a positive effect on catch-up growth in patients with growth disorders treated with growth hormone therapy.

de Arriba A, van Dommelen P, Savage M Front Endocrinol (Lausanne). 2024; 15:1450573.

PMID: 39429736 PMC: 11486743. DOI: 10.3389/fendo.2024.1450573.


Healthcare professionals' perspectives towards the digitalisation of paediatric growth hormone therapies: expert panels in Italy and Korea.

Rivera Romero O, Chae H, Faienza M, Vergani E, Cheon C, Di Mase R Front Endocrinol (Lausanne). 2024; 15:1419667.

PMID: 39050564 PMC: 11266127. DOI: 10.3389/fendo.2024.1419667.


The growzen™ buddy smartphone app to improve adherence in patients receiving recombinant human growth hormone therapy: a retrospective observational study in Argentina.

van Dommelen P, Arnaud L, Assefi A, Crespo M, Debicki M, Michelis F Front Endocrinol (Lausanne). 2024; 15:1372716.

PMID: 39015178 PMC: 11250275. DOI: 10.3389/fendo.2024.1372716.


References
1.
van Pareren Y, Mulder P, Houdijk M, Jansen M, Reeser M, Hokken-Koelega A . Effect of discontinuation of growth hormone treatment on risk factors for cardiovascular disease in adolescents born small for gestational age. J Clin Endocrinol Metab. 2003; 88(1):347-53. DOI: 10.1210/jc.2002-020458. View

2.
Arshad S, Arshad J, Khan M, Parkinson S . Analysis of security and privacy challenges for DNA-genomics applications and databases. J Biomed Inform. 2021; 119:103815. DOI: 10.1016/j.jbi.2021.103815. View

3.
Huang L, Guo H, Rao Q, Hou Z, Li S, Qiu S . Body Dimension Measurements of Qinchuan Cattle with Transfer Learning from LiDAR Sensing. Sensors (Basel). 2019; 19(22). PMC: 6891291. DOI: 10.3390/s19225046. View

4.
Bozzola M, Colle M, Halldin-Stenlid M, Larroque S, Zignani M . Treatment adherence with the easypod™ growth hormone electronic auto-injector and patient acceptance: survey results from 824 children and their parents. BMC Endocr Disord. 2011; 11:4. PMC: 3045978. DOI: 10.1186/1472-6823-11-4. View

5.
Boman N, Fernandez-Luque L, Koledova E, Kause M, Lapatto R . Connected health for growth hormone treatment research and clinical practice: learnings from different sources of real-world evidence (RWE)-large electronically collected datasets, surveillance studies and individual patients' cases. BMC Med Inform Decis Mak. 2021; 21(1):136. PMC: 8074467. DOI: 10.1186/s12911-021-01491-0. View