Systematic Evaluation of Cell-free Insulin DNA Levels in Early Blood Glucose Testing As a Predictor of Postpartum Hypertension in Pregnant Women with Gestational Diabetes Mellitus

Overview

Journal Am J Transl Res

Specialty General Medicine

Date 2022 Jul 15

PMID 35836844

Authors

Yuanyuan Zhang

Chunhua Li

Rui Lin

Yan Feng

Fang Zhang

Guangxia Zhang

Affiliations

Soon will be listed here.

Abstract

Objective: To investigate the perinatal outcome of postpartum hypertension in pregnant women with gestational diabetes (GDM).

Methods: A total of 100 puerperae who gave birth in our hospital from March 2018 to January 2020 were retrospectively analyzed. Among them, 50 patients were puerperae with postpartum hypertension (experimental group), and 50 puerperae had normal postpartum blood pressure (control group). Before delivery, fasting, postprandial and bedtime blood glucose, glycosylated hemoglobin, and urine glucose were compared between the two groups.

Results: Before delivery, the experimental group observed significantly higher fasting, postprandial, and bedtime blood glucose, glycosylated hemoglobin, and urine glucose than the control group (P<0.05). A notable decline in natural delivery rate was witnessed in the experimental group (P<0.05). The two groups presented no significant differences in neonatal outcomes, neonatal blood glucose and blood pressure, maternal blood pressure at 30 weeks and 34 weeks of pregnancy, and blood lipid levels during pregnancy (P>0.05).

Conclusion: Postpartum hypertension in pregnant women with GDM results in a low probability of natural birth and it has a slight impact on the fetus.

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