Sine Qua Non: Oncocytoma
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Oncocytomas of the salivary gland are uncommon neoplasms that are characterized by polygonal cells with abundant granular eosinophilic cytoplasm and relatively uniform nuclei. They are benign in nature and have a low recurrence rate with complete surgical excision. Though uncommon, oncocytic and clear cell variants of malignant tumors may histologically mimic oncocytomas and identification of their distinguishing features is essential. A classic example of an oncocytoma is discussed.
Salivary Gland Oncocytomas. A Systematic Review.
Alberto P, Ashim S, Megan K, Wei Z, Nestor G, Matthew Z Head Neck Pathol. 2024; 18(1):126.
PMID: 39614964 PMC: 11608208. DOI: 10.1007/s12105-024-01730-6.