Evidence for a Signal Peptide at the Amino-terminal End of Human Mitochondrial Aldehyde Dehydrogenase

Overview

Journal FEBS Lett

Specialty Biochemistry

Date 1987 May 11

PMID 3582651

Citations 16

Authors

T Braun

E Bober

S Singh

D P Agarwal

H W GOEDDE

Affiliations

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Abstract

A full-length cDNA clone coding for human mitochondrial aldehyde dehydrogenase (ALDH I) was isolated from a human fetal muscle cDNA library. Sequence analysis revealed structural similarities between the amino-terminal end of ALDH I and other known targeting sequences responsible for protein uptake into the mitochondria.

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