Splenic Infarctions in Polycythaemia Vera Are Not Always a Catastrophe

Overview

Journal Eur J Case Rep Intern Med

Specialty General Medicine

Date 2022 Jul 13

PMID 35821899

Authors

ElMustafa Abdalla

Muzamil Musa

Motwakil Musa

Ahmed Hatem

Abdalla Fadul

Ashraf Oe Ahmed

Affiliations

Soon will be listed here.

Abstract

Learning Points: Multiple splenic infarctions are an uncommon presentation in polycythaemia vera.Patients can present with vague abdominal pain, so a high index of suspicion is necessary and diagnosis is usually radiological.Splenic infarction in polycythaemia patients can be treated successfully with hydroxyurea and pain management with aspirin.

Citing Articles

Challenges in Diagnosing Polycythemia Vera in Primary Care: A 55-Year-Old Malaysian Woman with Atypical Presentation.

Haji Paiman N, Mat Nasir N, Miptah H, Saidon N, Abdul Monir M Am J Case Rep. 2024; 25:e944202.

PMID: 39262095 PMC: 11404705. DOI: 10.12659/AJCR.944202.

Primary polycythaemia: A neglected risk factor.

Rustogi N, Talapa R, Yadav J J Family Med Prim Care. 2024; 13(7):2772-2775.

PMID: 39071006 PMC: 11271991. DOI: 10.4103/jfmpc.jfmpc_1409_23.

Splenic infarction secondary to polycythemia Vera: Case report and literature review.

Abdoh Q, Alnees M, Rajab I, Zayed A, Salim H, Barqawi A Radiol Case Rep. 2023; 18(10):3636-3641.

PMID: 37593336 PMC: 10432139. DOI: 10.1016/j.radcr.2023.07.049.

References

Lim B . Clinics in diagnostic imaging (146). Polycythaemia vera (PV). Singapore Med J. 2013; 54(5):289-91. DOI: 10.11622/smedj.2013111. View

Inamdar S, Sangle S, Bote N, Nagargoje N . Splenic infarction in polycythaemia vera: can the spleen be saved?. J Assoc Physicians India. 2014; 62(3):276-8. View

Tefferi A, Rumi E, Finazzi G, Gisslinger H, Vannucchi A, Rodeghiero F . Survival and prognosis among 1545 patients with contemporary polycythemia vera: an international study. Leukemia. 2013; 27(9):1874-81. PMC: 3768558. DOI: 10.1038/leu.2013.163. View

Nores M, Phillips E, Morgenstern L, Hiatt J . The clinical spectrum of splenic infarction. Am Surg. 1998; 64(2):182-8. View

Ozakin E, Cetinkaya O, Baloglu Kaya F, Acar N, Cevik A . A Rare Cause of Acute Abdominal Pain: Splenic Infarct (Case Series). Turk J Emerg Med. 2016; 15(2):96-9. PMC: 4910014. DOI: 10.5505/1304.7361.2015.16769. View

Arber D, Orazi A, Hasserjian R, Thiele J, Borowitz M, Le Beau M . The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood. 2016; 127(20):2391-405. DOI: 10.1182/blood-2016-03-643544. View

Wellauer Atencio M, Goede J . [CME: Polycythemia vera]. Praxis (Bern 1994). 2019; 108(13):835-842. DOI: 10.1024/1661-8157/a003317. View

Griesshammer M, Kiladjian J, Besses C . Thromboembolic events in polycythemia vera. Ann Hematol. 2019; 98(5):1071-1082. PMC: 6469649. DOI: 10.1007/s00277-019-03625-x. View

Iurlo A, Cattaneo D, Bucelli C, Baldini L . New Perspectives on Polycythemia Vera: From Diagnosis to Therapy. Int J Mol Sci. 2020; 21(16). PMC: 7461104. DOI: 10.3390/ijms21165805. View

10.

Tefferi A, Vannucchi A, Barbui T . Polycythemia vera: historical oversights, diagnostic details, and therapeutic views. Leukemia. 2021; 35(12):3339-3351. PMC: 8632660. DOI: 10.1038/s41375-021-01401-3. View

11.

Sekhar M, McVinnie K, Burroughs A . Splanchnic vein thrombosis in myeloproliferative neoplasms. Br J Haematol. 2013; 162(6):730-47. DOI: 10.1111/bjh.12461. View