Evaluating the Non-conventional Achalasia Treatment Modalities

Overview

Journal Front Med (Lausanne)

Specialty General Medicine

Date 2022 Jul 11

PMID 35814742

Authors

Francisco Tustumi

Affiliations

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Abstract

Introduction: Achalasia is a primary esophageal dysmotility disorder. Despite the high volume of studies addressing the conventional treatments for achalasia, few are debated regarding the non-conventional treatments, such as cardiectomy, cardioplasty, endoluminal substances injection (ethanolamine oleate, polidocanol, botulinum toxin), stents, and certain drugs (beta-agonists, anticholinergic, nitrates, calcium channel blockers, and phosphodiesterase inhibitors).

Methods: A critical review was performed.

Results: Endoscopic, surgical, and pharmacological treatments were included. A qualitative synthesis was presented.

Conclusion: Non-conventional therapeutic options for treating achalasia encompass medical, endoscopic, and surgical procedures. Clinicians and patients need to know all the tools for the management of achalasia. However, several currently available studies of non-conventional treatments lack high-quality evidence, and future randomized trials are still needed.

Citing Articles

Serra doria procedure as an alternative treatment for end stage achalasia. A case report.

Zaafouri H, Cherif M, Khedhiri N, Sabbah M, Sabri T, Ben Maamer A Heliyon. 2024; 10(18):e37404.

PMID: 39315234 PMC: 11417681. DOI: 10.1016/j.heliyon.2024.e37404.

MANAGEMENT OF SYMPTOMS RECURRENCE AFTER MYOTOMY FOR ACHALASIA. A PRACTICAL APPROACH.

Tustumi F, Szachnowicz S, Andreollo N, Seguro F, Bianchi E, Duarte A Arq Bras Cir Dig. 2023; 36:e1780.

PMID: 38088726 PMC: 10712922. DOI: 10.1590/0102-672020230062e1780.

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