Gastrointestinal Complications of Intra-Abdominal Desmoid Tumors: A Case Report and Review of the Literature

Overview

Journal Case Rep Oncol

Publisher Karger

Specialty Oncology

Date 2022 Jul 11

PMID 35813700

Authors

Darcy Morris

Raquel Gonzalez

Jane Cook

Jonathan Metts

Peter Shaw

Affiliations

Soon will be listed here.

Abstract

A 15-year-old male with a mesenteric desmoid tumor and underlying familial adenomatous polyposis presented 2 weeks after initiating sorafenib with severe abdominal pain and chills and was found to have an acute abdomen. Exploratory laparotomy revealed a necrotic, ruptured tumor with impending small bowel obstruction. The patient was later able to resume sorafenib and experienced sustained a radiographic response. It is possible that sorafenib toxicity contributed to tumor rupture yet later provided clinical benefit. Here we review the gastrointestinal complications that are associated with intra-abdominal desmoid tumors and their therapies.

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