Multisite Biologic Tissue SARS-CoV-2 PCR Testing in Kidney Transplantation from a COVID-positive Donor
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With a high community transmission rate, SARS-CoV-2 has profoundly exacerbated the shortage of organs. Although the risk of donor-recipient transmission of SARS-CoV-2 is anecdotally low, an organ-specific infection analysis of procured organs from SARS-CoV-2 positive donors has yet to be established. Using a combination of clinically available and research-only polymerase chain reaction methods, organ preservation fluid and renal parenchymal tissues were tested for SARS-CoV-2 from the kidney of a SARS-CoV-2-positive donor prior to transplantation. The recipient has remained SARS-CoV-2 negative and clinically well, with excellent graft function 120 days post-transplantation.
The learning curve of COVID-19 and organ donation: Potential missed opportunities in the COVID era.
Zhang J, Mujtaba M, Wagenhauser H, Chapman Y, Engebretsen T, Stevenson H Heliyon. 2024; 10(11):e32086.
PMID: 38868064 PMC: 11168379. DOI: 10.1016/j.heliyon.2024.e32086.