Integrating Precision Medicine into the Standard of Care for Male Infertility: What Will It Take?

Overview

Journal Eur Urol

Specialty Urology

Date 2022 Jul 10

PMID 35811191

Authors

Jason Kunisaki

Aaron Quinlan

Kenneth I Aston

James Hotaling

Affiliations

Soon will be listed here.

Citing Articles

Identification and immuno-infiltration analysis of cuproptosis regulators in human spermatogenic dysfunction.

Zhao M, Yu W, Liu S, Deng Y, Zhao Z, Guo J Front Genet. 2023; 14:1115669.

PMID: 37065492 PMC: 10090386. DOI: 10.3389/fgene.2023.1115669.

Fertility in the aging male: a systematic review.

Jimbo M, Kunisaki J, Ghaed M, Yu V, Flores H, Hotaling J Fertil Steril. 2022; 118(6):1022-1034.

PMID: 36509505 PMC: 10914128. DOI: 10.1016/j.fertnstert.2022.10.035.

References

Wyrwoll M, Kockerling N, Vockel M, Dicke A, Rotte N, Pohl E . Genetic Architecture of Azoospermia-Time to Advance the Standard of Care. Eur Urol. 2022; 83(5):452-462. DOI: 10.1016/j.eururo.2022.05.011. View

Oud M, Volozonoka L, Smits R, Vissers L, Ramos L, Veltman J . A systematic review and standardized clinical validity assessment of male infertility genes. Hum Reprod. 2019; 34(5):932-941. PMC: 6505449. DOI: 10.1093/humrep/dez022. View

Sen N, Anishchenko I, Bordin N, Sillitoe I, Velankar S, Baker D . Characterizing and explaining the impact of disease-associated mutations in proteins without known structures or structural homologs. Brief Bioinform. 2022; 23(4). PMC: 9294430. DOI: 10.1093/bib/bbac187. View

Parvez S, Herdman C, Beerens M, Chakraborti K, Harmer Z, Yeh J . MIC-Drop: A platform for large-scale in vivo CRISPR screens. Science. 2021; 373(6559):1146-1151. PMC: 9083377. DOI: 10.1126/science.abi8870. View

Hotaling J, Carrell D . Clinical genetic testing for male factor infertility: current applications and future directions. Andrology. 2014; 2(3):339-50. DOI: 10.1111/j.2047-2927.2014.00200.x. View

Baek M, Baker D . Deep learning and protein structure modeling. Nat Methods. 2022; 19(1):13-14. DOI: 10.1038/s41592-021-01360-8. View

Wu W, Shen O, Qin Y, Niu X, Lu C, Xia Y . Idiopathic male infertility is strongly associated with aberrant promoter methylation of methylenetetrahydrofolate reductase (MTHFR). PLoS One. 2010; 5(11):e13884. PMC: 2976703. DOI: 10.1371/journal.pone.0013884. View

Cocuzza M, Alvarenga C, Pagani R . The epidemiology and etiology of azoospermia. Clinics (Sao Paulo). 2013; 68 Suppl 1:15-26. PMC: 3583160. DOI: 10.6061/clinics/2013(sup01)03. View

Bernie A, Mata D, Ramasamy R, Schlegel P . Comparison of microdissection testicular sperm extraction, conventional testicular sperm extraction, and testicular sperm aspiration for nonobstructive azoospermia: a systematic review and meta-analysis. Fertil Steril. 2015; 104(5):1099-103.e1-3. DOI: 10.1016/j.fertnstert.2015.07.1136. View

10.

Houston B, Riera-Escamilla A, Wyrwoll M, Salas-Huetos A, Xavier M, Nagirnaja L . A systematic review of the validated monogenic causes of human male infertility: 2020 update and a discussion of emerging gene-disease relationships. Hum Reprod Update. 2021; 28(1):15-29. PMC: 8730311. DOI: 10.1093/humupd/dmab030. View