Incidence and Risk Factors for Berger's Space Development After Uneventful Cataract Surgery: Evidence from Swept-Source Optical Coherence Tomography

Overview

Journal J Clin Med

Specialty General Medicine

Date 2022 Jul 9

PMID 35806863

Authors

Zhengwei Zhang

Jinhan Yao

Shuimiao Chang

Piotr Kanclerz

Ramin Khoramnia

Minghui Deng

Xiaogang Wang

Affiliations

Soon will be listed here.

Abstract

Background: This study investigates the incidence and risk factors for the development of Berger’s space (BS) after uneventful phacoemulsification based on swept-source optical coherence tomography (SS-OCT). Methods: Cataractous eyes captured using qualified SS-OCT images before and after uneventful phacoemulsification cataract surgery were included. Six high-resolution cross-sectional anterior segment SS-OCT images at 30° intervals were used for BS data measurements. BS width was measured at three points on each scanned meridian line: the central point line aligned with the cornea vertex and two point lines at the pupil’s margins. Results: A total of 223 eyes that underwent uneventful cataract surgery were evaluated. Preoperatively, only two eyes (2/223, 0.9%) were observed to have consistent BS in all six scanning directions. BS was observed postoperatively in 44 eyes (44/223, 19.7%). A total of 13 eyes (13/223, 5.8%) with insufficient image quality, pupil dilation, or lack of preoperative image data were excluded from the study. A total of 31 postoperative eyes with BS and 31 matched eyes without BS were included in the final data analysis. The smallest postoperative BS width was in the upper quadrant of the vertical meridian line (90°), with a mean value of 280 μm. The largest BS width was observed in the opposite area of the main clear corneal incision, with a mean value >500 μm. Conclusions: Uneven-width BS is observable after uneventful phacoemulsification. Locations with a much wider BS (indirect manifestation of Wieger zonular detachment) are predominantly located in the opposite direction to the main corneal incisions.

Citing Articles

Investigation of 3D iris morphology early alteration after implantable collamer lens implantation by using SS-OCT.

Zhang Z, Chang S, Li K, Yao J, Wang Z, Liu J Heliyon. 2025; 11(1):e41542.

PMID: 39844973 PMC: 11750528. DOI: 10.1016/j.heliyon.2024.e41542.

Research progress in Berger's space: An interesting retrolenticular space.

Xu Y, Zhang Z, Deng M, Wang X Heliyon. 2025; 10(22):e40432.

PMID: 39748980 PMC: 11693895. DOI: 10.1016/j.heliyon.2024.e40432.

Examination of Vitreolenticular Interface in Relation to Different Phacoemulsification Parameters in Early and Late Postoperative Period.

Elekes A, Vamosi P J Clin Med. 2024; 13(16).

PMID: 39200997 PMC: 11355322. DOI: 10.3390/jcm13164855.

Examination of the Vitreolenticular Interface in Relation to Uneventful Phacoemulsification over One-Year Postoperative Period.

Elekes A, Nemeth G, Lauter D, Edelmayer M, Rupnik Z, Vamosi P J Clin Med. 2024; 13(11).

PMID: 38892935 PMC: 11173090. DOI: 10.3390/jcm13113219.

Editorial: Imaging in Ophthalmology.

Ferrara M, Zheng Y, Romano V J Clin Med. 2022; 11(18).

PMID: 36143079 PMC: 9503085. DOI: 10.3390/jcm11185433.

References

Montes-Mico R, Pastor-Pascual F, Ruiz-Mesa R, Tana-Rivero P . Ocular biometry with swept-source optical coherence tomography. J Cataract Refract Surg. 2020; 47(6):802-814. DOI: 10.1097/j.jcrs.0000000000000551. View

Tassignon M, Dhubhghaill S . Real-Time Intraoperative Optical Coherence Tomography Imaging Confirms Older Concepts About the Berger Space. Ophthalmic Res. 2016; 56(4):222-226. DOI: 10.1159/000446242. View

Menapace R . Posterior capsulorhexis combined with optic buttonholing: an alternative to standard in-the-bag implantation of sharp-edged intraocular lenses? A critical analysis of 1000 consecutive cases. Graefes Arch Clin Exp Ophthalmol. 2008; 246(6):787-801. PMC: 2367393. DOI: 10.1007/s00417-008-0779-6. View

TOLENTINO F, Lee P, Schepens C . Biomicroscopic study of vitreous cavity in diabetic retinopathy. Arch Ophthalmol. 1966; 75(2):238-46. DOI: 10.1001/archopht.1966.00970050240018. View

Dubrulle P, Fajnkuchen F, Qu L, Giocanti-Auregan A . Dexamethasone implant confined in Berger's space. Springerplus. 2016; 5(1):1786. PMC: 5063824. DOI: 10.1186/s40064-016-3490-9. View

Weidle E . Visualization of Berger's space in the living eye. Ophthalmic Surg. 1985; 16(11):733-4. View

Turgut B, Turkcuoglu P, Deniz N, Catak O . Annular and central heavy pigment deposition on the posterior lens capsule in the pigment dispersion syndrome: pigment deposition on the posterior lens capsule in the pigment dispersion syndrome. Int Ophthalmol. 2007; 28(6):441-5. DOI: 10.1007/s10792-007-9158-2. View

Santos-Bueso E . Berger's space. Arch Soc Esp Oftalmol (Engl Ed). 2019; 94(10):471-477. DOI: 10.1016/j.oftal.2019.06.006. View

Li S, Yiu E, Wong A, Yeung J, Yu L . Management of traumatic haemorrhage in the Berger's space of a 4-year-old child. Int Ophthalmol. 2016; 37(4):1053-1055. DOI: 10.1007/s10792-016-0337-x. View

10.

Pujari A, Agarwal D, Sharma N . Clinical role of swept source optical coherence tomography in anterior segment diseases: a review. Semin Ophthalmol. 2021; 36(8):684-691. DOI: 10.1080/08820538.2021.1897854. View

11.

Lyu J, Zhang Q, Zhao P . Viscodelamination of Localized Retrolental Plaques During Lens-Sparing Vitrectomy in Eyes With Pediatric Tractional Vitreoretinopathy. Retina. 2020; 43(3):523-528. PMC: 9935560. DOI: 10.1097/IAE.0000000000002834. View

12.

Schlotzer-Schrehardt U, Naumann G . A histopathologic study of zonular instability in pseudoexfoliation syndrome. Am J Ophthalmol. 1994; 118(6):730-43. DOI: 10.1016/s0002-9394(14)72552-8. View

13.

Dick H, Schultz T . Primary posterior laser-assisted capsulotomy. J Refract Surg. 2014; 30(2):128-33. DOI: 10.3928/1081597X-20140120-09. View

14.

Anisimova N, Arbisser L, Shilova N, Melnik M, Belodedova A, Knyazer B . Anterior vitreous detachment: risk factor for intraoperative complications during phacoemulsification. J Cataract Refract Surg. 2020; 46(1):55-62. DOI: 10.1016/j.jcrs.2019.08.005. View

15.

Haeussler-Sinangin Y, Schultz T, Holtmann E, Dick H . Primary posterior capsulotomy in femtosecond laser-assisted cataract surgery: In vivo spectral-domain optical coherence tomography study. J Cataract Refract Surg. 2016; 42(9):1339-1344. DOI: 10.1016/j.jcrs.2016.06.037. View

16.

Mares V, Nehemy M, Salomao D, Goddard S, Tesmer J, Pulido J . Multimodal Imaging and Histopathological Evaluation of Berger's Space. Ocul Oncol Pathol. 2020; 6(1):3-9. PMC: 6984151. DOI: 10.1159/000495724. View

17.

Dong J, Wang X, Deng M, Wang X . Three-Dimensional Reconstruction and Swept-Source Optical Coherence Tomography for Crystalline Lens Tilt and Decentration Relative to the Corneal Vertex. Transl Vis Sci Technol. 2021; 10(9):13. PMC: 8363763. DOI: 10.1167/tvst.10.9.13. View

18.

Lains I, Wang J, Cui Y, Katz R, Vingopoulos F, Staurenghi G . Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA). Prog Retin Eye Res. 2021; 84:100951. DOI: 10.1016/j.preteyeres.2021.100951. View

19.

Park J, Yang H, Kwon H, Jeon S . Risk Factors for Onset or Progression of Posterior Vitreous Detachment at the Vitreomacular Interface after Cataract Surgery. Ophthalmol Retina. 2020; 5(3):270-278. DOI: 10.1016/j.oret.2020.07.017. View

20.

Menapace R . Transzonular capsulo-hyaloidal hydroseparation with optional triamcinolone enhancement: A technique to detect or induce anterior hyaloid membrane detachment for primary posterior laser capsulotomy. J Cataract Refract Surg. 2019; 45(7):903-909. DOI: 10.1016/j.jcrs.2019.03.008. View