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Impact of Pelvic Anatomical Changes Caused by Radical Prostatectomy

Overview
Journal Cancers (Basel)
Publisher MDPI
Specialty Oncology
Date 2022 Jul 9
PMID 35804823
Authors
Affiliations
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Abstract

During radical prostatectomy, the prostate is removed along with the seminal vesicles, and the urinary tract is reconstructed by dropping the bladder onto the pelvic floor and suturing the bladder and urethra together. This process causes damage to the pelvic floor and postoperative complications due to the anatomical changes in the pelvic floor caused by the vesicourethral anastomosis. Urinary incontinence and erectile dysfunction are major complications that impair patients' quality of life after radical prostatectomy. In addition, the shortening of the penis and the increased prevalence of inguinal hernia have been reported. Since these postoperative complications subsequently affect patients' quality of life, their reduction is a matter of great interest, and procedural innovations such as nerve-sparing techniques, Retzius space preservation, and inguinal hernia prophylaxis have been developed. It is clear that nerve sparing is useful for preserving the erectile function, and nerve sparing, urethral length preservation, and Retzius sparing are useful for urinary continence. The evaluation of pre- and postoperative imaging to observe changes in pelvic anatomy is also beginning to clarify why these techniques are useful. Changes in pelvic anatomy after radical prostatectomy are inevitable and, therefore, postoperative complications cannot be completely eliminated; however, preserving as much of the tissue and structure around the prostate as possible, to the extent that prostate cancer control is not compromised, may help reduce the prevalence of postoperative complications.

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References
1.
Menon M, Muhletaler F, Campos M, Peabody J . Assessment of early continence after reconstruction of the periprostatic tissues in patients undergoing computer assisted (robotic) prostatectomy: results of a 2 group parallel randomized controlled trial. J Urol. 2008; 180(3):1018-23. DOI: 10.1016/j.juro.2008.05.046. View

2.
Menon M, Dalela D, Jamil M, Diaz M, Tallman C, Abdollah F . Functional Recovery, Oncologic Outcomes and Postoperative Complications after Robot-Assisted Radical Prostatectomy: An Evidence-Based Analysis Comparing the Retzius Sparing and Standard Approaches. J Urol. 2017; 199(5):1210-1217. DOI: 10.1016/j.juro.2017.11.115. View

3.
Schlomm T, Heinzer H, Steuber T, Salomon G, Engel O, Michl U . Full functional-length urethral sphincter preservation during radical prostatectomy. Eur Urol. 2011; 60(2):320-9. DOI: 10.1016/j.eururo.2011.02.040. View

4.
Stafford R, van den Hoorn W, Coughlin G, Hodges P . Postprostatectomy incontinence is related to pelvic floor displacements observed with trans-perineal ultrasound imaging. Neurourol Urodyn. 2017; 37(2):658-665. DOI: 10.1002/nau.23371. View

5.
Patel V, Schatloff O, Chauhan S, Sivaraman A, Valero R, Coelho R . The role of the prostatic vasculature as a landmark for nerve sparing during robot-assisted radical prostatectomy. Eur Urol. 2012; 61(3):571-6. DOI: 10.1016/j.eururo.2011.12.047. View