Effects of COVID-19 During Pregnancy on Maternal and Neonatal Outcome: A Retrospective Observational Study in Tertiary Teaching Hospital, India
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Aim: This study aims to describe the clinical characteristics, maternal and neonatal outcome of pregnancies complicated with COVID-19 infection.
Methods: This is a retrospective, single center, observational study conducted on all COVID-19 positive pregnant women who were admitted in our institution from 1 April 2020 to 30 November 2020. During the study period, a total of 201 pregnant and postpartum women with COVID-19 infection confirmed by RT-PCR test, regardless of their symptoms, were admitted and included in the study. Data were collected from hospital records about the demographic profile, clinical characteristics, maternal and neonatal outcomes.
Results: The mean age was 26 years (SD = 5.21). Majority patients (71.6%) were asymptomatic and 22.3% had mild symptoms. Only 4 (1.99%) women had severe COVID pneumonia. Majority (75.62%) were admitted in 3 trimester. Cesarean section rate in COVID-19 infected pregnant women was 53.8%, which was almost similar to 52.8% rate in COVID-19 negative pregnant population. Incidence of preterm birth was 11%. Most neonate were asymptomatic and only 2 of them tested positive on testing within 48 h of birth.
Conclusion: There is no major effect of COVID-19 infection during pregnancy on maternal and neonatal outcome. The incidence of preterm birth and cesarean section is similar to COVID-19 negative pregnant population.
Li J, Li X, Ye P, You Y, Wang Y, Zhang J PeerJ. 2023; 11:e16651.
PMID: 38107588 PMC: 10725666. DOI: 10.7717/peerj.16651.
van Baar J, Kostova E, Allotey J, Thangaratinam S, Zamora J, Bonet M Hum Reprod Update. 2023; 30(2):133-152.
PMID: 38016805 PMC: 10905512. DOI: 10.1093/humupd/dmad030.