» Articles » PMID: 35800513

Effects of COVID-19 During Pregnancy on Maternal and Neonatal Outcome: A Retrospective Observational Study in Tertiary Teaching Hospital, India

Overview
Specialty Public Health
Date 2022 Jul 8
PMID 35800513
Authors
Affiliations
Soon will be listed here.
Abstract

Aim: This study aims to describe the clinical characteristics, maternal and neonatal outcome of pregnancies complicated with COVID-19 infection.

Methods: This is a retrospective, single center, observational study conducted on all COVID-19 positive pregnant women who were admitted in our institution from 1 April 2020 to 30 November 2020. During the study period, a total of 201 pregnant and postpartum women with COVID-19 infection confirmed by RT-PCR test, regardless of their symptoms, were admitted and included in the study. Data were collected from hospital records about the demographic profile, clinical characteristics, maternal and neonatal outcomes.

Results: The mean age was 26 years (SD = 5.21). Majority patients (71.6%) were asymptomatic and 22.3% had mild symptoms. Only 4 (1.99%) women had severe COVID pneumonia. Majority (75.62%) were admitted in 3 trimester. Cesarean section rate in COVID-19 infected pregnant women was 53.8%, which was almost similar to 52.8% rate in COVID-19 negative pregnant population. Incidence of preterm birth was 11%. Most neonate were asymptomatic and only 2 of them tested positive on testing within 48 h of birth.

Conclusion: There is no major effect of COVID-19 infection during pregnancy on maternal and neonatal outcome. The incidence of preterm birth and cesarean section is similar to COVID-19 negative pregnant population.

Citing Articles

A retrospective observational study on maternal and neonatal outcomes of COVID-19: Does the mild SARS-CoV-2 infection affect the outcome?.

Li J, Li X, Ye P, You Y, Wang Y, Zhang J PeerJ. 2023; 11:e16651.

PMID: 38107588 PMC: 10725666. DOI: 10.7717/peerj.16651.


COVID-19 in pregnant women: a systematic review and meta-analysis on the risk and prevalence of pregnancy loss.

van Baar J, Kostova E, Allotey J, Thangaratinam S, Zamora J, Bonet M Hum Reprod Update. 2023; 30(2):133-152.

PMID: 38016805 PMC: 10905512. DOI: 10.1093/humupd/dmad030.

References
1.
Salvatore C, Han J, Acker K, Tiwari P, Jin J, Brandler M . Neonatal management and outcomes during the COVID-19 pandemic: an observation cohort study. Lancet Child Adolesc Health. 2020; 4(10):721-727. PMC: 7377726. DOI: 10.1016/S2352-4642(20)30235-2. View

2.
Schwartz D, Graham A . Potential Maternal and Infant Outcomes from (Wuhan) Coronavirus 2019-nCoV Infecting Pregnant Women: Lessons from SARS, MERS, and Other Human Coronavirus Infections. Viruses. 2020; 12(2). PMC: 7077337. DOI: 10.3390/v12020194. View

3.
Knight M, Bunch K, Vousden N, Morris E, Simpson N, Gale C . Characteristics and outcomes of pregnant women admitted to hospital with confirmed SARS-CoV-2 infection in UK: national population based cohort study. BMJ. 2020; 369:m2107. PMC: 7277610. DOI: 10.1136/bmj.m2107. View

4.
Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W . Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet. 2020; 395(10226):809-815. PMC: 7159281. DOI: 10.1016/S0140-6736(20)30360-3. View

5.
Ronchi A, Pietrasanta C, Zavattoni M, Saruggia M, Schena F, Sinelli M . Evaluation of Rooming-in Practice for Neonates Born to Mothers With Severe Acute Respiratory Syndrome Coronavirus 2 Infection in Italy. JAMA Pediatr. 2020; 175(3):260-266. PMC: 7921895. DOI: 10.1001/jamapediatrics.2020.5086. View