Improvement in Lung Function with Dupilumab Does Not Predict Its Effects on Reducing Asthma Exacerbation

Overview

Journal J Asthma Allergy

Publisher Dove Medical Press

Date 2022 Jul 5

PMID 35789920

Authors

Nicola A Hanania

Jorge F Maspero

David M G Halpin

David J Jackson

Reynold A Panettieri

Mario Castro

Christian Domingo

Nadia Daizadeh

Rebecca Gall

Juby A Jacob-Nara

Benjamin Ortiz

Michel Djandji

Paul J Rowe

Yamo Deniz

Affiliations

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Citing Articles

Impact of Lung Function on Asthma Exacerbation Rates in Children Treated with Dupilumab: The VOYAGE Study.

Guilbert T, Murphy K, Hamelmann E, Ross K, Gupta A, Fiocchi A J Asthma Allergy. 2024; 17:81-87.

PMID: 38347908 PMC: 10860392. DOI: 10.2147/JAA.S425101.

References

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Tepper R, Wise R, Covar R, Irvin C, Kercsmar C, Kraft M . Asthma outcomes: pulmonary physiology. J Allergy Clin Immunol. 2012; 129(3 Suppl):S65-87. PMC: 4263032. DOI: 10.1016/j.jaci.2011.12.986. View

Castro M, Corren J, Pavord I, Maspero J, Wenzel S, Rabe K . Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma. N Engl J Med. 2018; 378(26):2486-2496. DOI: 10.1056/NEJMoa1804092. View

Castro M, Rabe K, Corren J, Pavord I, Katelaris C, Tohda Y . Dupilumab improves lung function in patients with uncontrolled, moderate-to-severe asthma. ERJ Open Res. 2020; 6(1). PMC: 6983496. DOI: 10.1183/23120541.00204-2019. View