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Advances in Biomarkers and Techniques for Pancreatic Cancer Diagnosis

Overview
Journal Cancer Cell Int
Publisher Biomed Central
Date 2022 Jun 27
PMID 35761336
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Abstract

Pancreatic cancer is the most lethal type of malignancy and is characterized by high invasiveness without severe symptoms. It is difficult to detect PC at an early stage because of the low diagnostic accuracy of existing routine methods, such as abdominal ultrasound, CT, MRI, and endoscopic ultrasound (EUS). Therefore, it is of value to develop new diagnostic techniques for early detection with high accuracy. In this review, we aim to highlight research progress on novel biomarkers, artificial intelligence, and nanomaterial applications on the diagnostic accuracy of pancreatic cancer.

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References
1.
Fattahi R, Balci N, Perman W, Hsueh E, AlKaade S, Havlioglu N . Pancreatic diffusion-weighted imaging (DWI): comparison between mass-forming focal pancreatitis (FP), pancreatic cancer (PC), and normal pancreas. J Magn Reson Imaging. 2009; 29(2):350-6. DOI: 10.1002/jmri.21651. View

2.
Yi J, Guzzetta A, Bailey V, Downing S, Van Neste L, Chiappinelli K . Novel methylation biomarker panel for the early detection of pancreatic cancer. Clin Cancer Res. 2013; 19(23):6544-6555. PMC: 4310572. DOI: 10.1158/1078-0432.CCR-12-3224. View

3.
Yang J, Sun Y, Liu D, Zhang J, Li J, Hua R . MicroRNAs in stool samples as potential screening biomarkers for pancreatic ductal adenocarcinoma cancer. Am J Cancer Res. 2014; 4(6):663-73. PMC: 4266702. View

4.
Li L, Zhang G, Chen H, Zhao Z, Chen H, Liu H . Plasma and tumor levels of Linc-pint are diagnostic and prognostic biomarkers for pancreatic cancer. Oncotarget. 2016; 7(44):71773-71781. PMC: 5342121. DOI: 10.18632/oncotarget.12365. View

5.
Das A, Nguyen C, Li F, Li B . Digital image analysis of EUS images accurately differentiates pancreatic cancer from chronic pancreatitis and normal tissue. Gastrointest Endosc. 2008; 67(6):861-7. DOI: 10.1016/j.gie.2007.08.036. View