Impact of Sleep Apnea and Treatments on Cardiovascular Disease

Overview

Journal Sleep Sci

Publisher Thieme

Date 2022 Jun 27

PMID 35755909

Authors

Andre Faria

Arthur Macedo

Carolina Castro

Elke Valle

Raquel Lacerda

Najib Ayas

Ismail Laher

Affiliations

Soon will be listed here.

Abstract

Cardiovascular diseases (CVDs) are the leading causes of mortality worldwide, accounting for nearly 18 million deaths per year. Among other considerations, treating CVDs requires better understanding their risk factors. Sleep-disordered breathing, especially obstructive sleep apnea (OSA), is a likely contributor to several CVDs. We review key epidemiological data that addresses the link between OSA and cardiovascular outcomes such as hypertension, atrial fibrillation (AF), stroke, atherosclerosis, and heart failure (HF), and proposed pathophysiological mechanisms underlying this association. There are several biological pathways linking OSA and an increased propensity to cardiovascular diseases, and we discuss the evidence on the benefits of treatments of OSA on the prevalence of cardiovascular complications.

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