Exposure to Asbestos and Increased Intrahepatic Cholangiocarcinoma Risk: Growing Evidences of a Putative Causal Link

Overview

Journal Ann Glob Health

Publisher Ubiquity Press

Specialties General Medicine
Public Health

Date 2022 Jun 27

PMID 35755315

Authors

Giovanni Brandi

Kurt Straif

Daniele Mandrioli

Stefania Curti

Stefano Mattioli

Simona Tavolari

Affiliations

Soon will be listed here.

Abstract

To date the true global incidence of intrahepatic cholangiocarcinoma (iCCA) and the underlying risk factors remain to be fully defined, in particular, the role of occupational and environmental factors. Currently, the putative role of asbestos exposure as a risk factor for iCCA is gaining increased attention in the international scientific community and agencies. In this commentary we review and integrate available epidemiological and mechanistic evidences that support a potential role of asbestos exposure in iCCA etiology.

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