Chitosan: A Sustainable Material for Multifarious Applications

Overview

Journal Polymers (Basel)

Publisher MDPI

Date 2022 Jun 24

PMID 35745912

Authors

Abdul Zubar Hameed

Sakthivel Aravind Raj

Jayakrishna Kandasamy

Majed Abubakr Baghdadi

Muhammad Atif Shahzad

Affiliations

Soon will be listed here.

Abstract

Due to the versatility of its features and capabilities, chitosan generated from marine crustacean waste is gaining importance and appeal in a wide variety of applications. It was initially used in pharmaceutical and medical applications due to its antibacterial, biocompatible, and biodegradable properties. However, as the demand for innovative materials with environmentally benign properties has increased, the application range of chitosan has expanded, and it is now used in a variety of everyday applications. The most exciting aspect of the chitosan is its bactericidal properties against pathogens, which are prevalent in contaminated water and cause a variety of human ailments. Apart from antimicrobial and water filtration applications, chitosan is used in dentistry, in water filtration membranes to remove metal ions and some heavy metals from industrial effluents, in microbial fuel cell membranes, and in agriculture to maintain moisture in fruits and leaves. It is also used in skin care products and cosmetics as a moisturizer, in conjunction with fertilizer to boost plant immunity, and as a bi-adhesive for bonding woods and metals. As it has the capacity to increase the life span of food items and raw meat, it is an unavoidable component in food packing and preservation. The numerous applications of chitosan are reviewed in this brief study, as well as the approaches used to incorporate chitosan alongside traditional materials and its effect on the outputs.

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References

Shahrajabian M, Chaski C, Polyzos N, Tzortzakis N, Petropoulos S . Sustainable Agriculture Systems in Vegetable Production Using Chitin and Chitosan as Plant Biostimulants. Biomolecules. 2021; 11(6). PMC: 8226918. DOI: 10.3390/biom11060819. View

Karthikeyan C, Varaprasad K, Akbari-Fakhrabadi A, Hameed A, Sadiku R . Biomolecule chitosan, curcumin and ZnO-based antibacterial nanomaterial, via a one-pot process. Carbohydr Polym. 2020; 249:116825. DOI: 10.1016/j.carbpol.2020.116825. View

Qasim S, Zafar M, Najeeb S, Khurshid Z, Shah A, Husain S . Electrospinning of Chitosan-Based Solutions for Tissue Engineering and Regenerative Medicine. Int J Mol Sci. 2018; 19(2). PMC: 5855629. DOI: 10.3390/ijms19020407. View

Senthilkumar R, Bhuvaneshwari V, Ranjithkumar R, Sathiyavimal S, Malayaman V, Chandarshekar B . Synthesis, characterization and antibacterial activity of hybrid chitosan-cerium oxide nanoparticles: As a bionanomaterials. Int J Biol Macromol. 2017; 104(Pt B):1746-1752. DOI: 10.1016/j.ijbiomac.2017.03.139. View

Nayl A, Abd-Elhamid A, Awwad N, Abdelgawad M, Wu J, Mo X . Review of the Recent Advances in Electrospun Nanofibers Applications in Water Purification. Polymers (Basel). 2022; 14(8). PMC: 9025395. DOI: 10.3390/polym14081594. View

Fuster M, Montalban M, Carissimi G, Lima B, Feresin G, Cano M . Antibacterial Effect of Chitosan-Gold Nanoparticles and Computational Modeling of the Interaction between Chitosan and a Lipid Bilayer Model. Nanomaterials (Basel). 2020; 10(12). PMC: 7761461. DOI: 10.3390/nano10122340. View

Sharifianjazi F, Khaksar S, Esmaeilkhanian A, Bazli L, Eskandarinezhad S, Salahshour P . Advancements in Fabrication and Application of Chitosan Composites in Implants and Dentistry: A Review. Biomolecules. 2022; 12(2). PMC: 8961661. DOI: 10.3390/biom12020155. View

Meng Q, Sun Y, Cong H, Hu H, Xu F . An overview of chitosan and its application in infectious diseases. Drug Deliv Transl Res. 2021; 11(4):1340-1351. PMC: 7837079. DOI: 10.1007/s13346-021-00913-w. View

Zienkiewicz-Strzalka M, Derylo-Marczewska A, Skorik Y, Petrova V, Choma A, Komaniecka I . Silver Nanoparticles on Chitosan/Silica Nanofibers: Characterization and Antibacterial Activity. Int J Mol Sci. 2019; 21(1). PMC: 6981428. DOI: 10.3390/ijms21010166. View

10.

Jaber N, Al-Remawi M, Al-Akayleh F, Al-Muhtaseb N, Al-Adham I, Collier P . A review of the antiviral activity of Chitosan, including patented applications and its potential use against COVID-19. J Appl Microbiol. 2021; 132(1):41-58. PMC: 8447037. DOI: 10.1111/jam.15202. View

11.

Gadkari R, Ali S, Joshi M, Rajendran S, Das A, Alagirusamy R . Leveraging antibacterial efficacy of silver loaded chitosan nanoparticles on layer-by-layer self-assembled coated cotton fabric. Int J Biol Macromol. 2020; 162:548-560. DOI: 10.1016/j.ijbiomac.2020.06.137. View

12.

Jiang L, Luo Z, Liu H, Wang F, Li H, Gao H . Preparation and Characterization of Chitosan Films Containing Lychee ( Sonn.) Pericarp Powder and Their Application as Active Food Packaging. Foods. 2021; 10(11). PMC: 8620354. DOI: 10.3390/foods10112834. View

13.

Jayaramudu T, Varaprasad K, Pyarasani R, Koteshwara Reddy K, Kumar K, Akbari-Fakhrabadi A . Chitosan capped copper oxide/copper nanoparticles encapsulated microbial resistant nanocomposite films. Int J Biol Macromol. 2019; 128:499-508. DOI: 10.1016/j.ijbiomac.2019.01.145. View

14.

Zhou X, Yin A, Sheng J, Wang J, Chen H, Fang Y . In situ deposition of nano CuO on electrospun chitosan nanofibrous scaffolds and their antimicrobial properties. Int J Biol Macromol. 2021; 191:600-607. DOI: 10.1016/j.ijbiomac.2021.09.121. View

15.

Wang G, Li R, Parseh B, Du G . Prospects and challenges of anticancer agents' delivery via chitosan-based drug carriers to combat breast cancer: a review. Carbohydr Polym. 2021; 268:118192. DOI: 10.1016/j.carbpol.2021.118192. View

16.

Gao Y, Wu Y . Recent advances of chitosan-based nanoparticles for biomedical and biotechnological applications. Int J Biol Macromol. 2022; 203:379-388. DOI: 10.1016/j.ijbiomac.2022.01.162. View

17.

Yin N, Du R, Zhao F, Han Y, Zhou Z . Characterization of antibacterial bacterial cellulose composite membranes modified with chitosan or chitooligosaccharide. Carbohydr Polym. 2019; 229:115520. DOI: 10.1016/j.carbpol.2019.115520. View

18.

Belbekhouche S, Bousserrhine N, Alphonse V, Le Floch F, Charif Mechiche Y, Menidjel I . Chitosan based self-assembled nanocapsules as antibacterial agent. Colloids Surf B Biointerfaces. 2019; 181:158-165. DOI: 10.1016/j.colsurfb.2019.05.028. View

19.

Biao L, Tan S, Wang Y, Guo X, Fu Y, Xu F . Synthesis, characterization and antibacterial study on the chitosan-functionalized Ag nanoparticles. Mater Sci Eng C Mater Biol Appl. 2017; 76:73-80. DOI: 10.1016/j.msec.2017.02.154. View

20.

Cheah W, Show P, Ng I, Lin G, Chiu C, Chang Y . Antibacterial activity of quaternized chitosan modified nanofiber membrane. Int J Biol Macromol. 2018; 126:569-577. DOI: 10.1016/j.ijbiomac.2018.12.193. View