Where Do We Stand in the Behavioral Pathogenesis of Inflammatory Bowel Disease? The Western Dietary Pattern and Microbiota-A Narrative Review

Overview

Journal Nutrients

Date 2022 Jun 24

PMID 35745251

Authors

Iwona Krela-Kazmierczak

Oliwia Zakerska-Banaszak

Marzena Skrzypczak-Zielinska

Liliana Lykowska-Szuber

Aleksandra Szymczak-Tomczak

Agnieszka Zawada

Anna Maria Rychter

Alicja Ewa Ratajczak

Kinga Skoracka

Dorota Skrzypczak

Emilia Marcinkowska

Ryszard Slomski

Agnieszka Dobrowolska

Affiliations

Soon will be listed here.

Abstract

Despite the increasing knowledge with regard to IBD (inflammatory bowel disease), including ulcerative colitis (UC) and Crohn's disease (CD), the etiology of these conditions is still not fully understood. Apart from immunological, environmental and nutritional factors, which have already been well documented, it is worthwhile to look at the possible impact of genetic factors, as well as the composition of the microbiota in patients suffering from IBD. New technologies in biochemistry allow to obtain information that can add to the current state of knowledge in IBD etiology.

Citing Articles

Unveiling and Validating the Role of Fatty Acid Metabolism in Ulcerative Colitis.

Deng B, Zhen J, Xiang Z, Li X, Tan C, Chen Y J Inflamm Res. 2024; 17:6345-6362.

PMID: 39291081 PMC: 11407323. DOI: 10.2147/JIR.S479011.

The Role of Host Genetics and Intestinal Microbiota and Metabolome as a New Insight into IBD Pathogenesis.

Zakerska-Banaszak O, Zuraszek-Szymanska J, Eder P, Ladziak K, Slomski R, Skrzypczak-Zielinska M Int J Mol Sci. 2024; 25(17).

PMID: 39273536 PMC: 11394875. DOI: 10.3390/ijms25179589.

Exploring the theranostic potentials of miRNA and epigenetic networks in autoimmune diseases: A comprehensive review.

Nag S, Mitra O, Tripathi G, Samanta S, Bhattacharya B, Chandane P Immun Inflamm Dis. 2023; 11(12):e1121.

PMID: 38156400 PMC: 10755504. DOI: 10.1002/iid3.1121.

Bile acids and their receptors: Potential therapeutic targets in inflammatory bowel disease.

Long X, Liu M, Liu Z, Xia L, Lu S, Xu X World J Gastroenterol. 2023; 29(27):4252-4270.

PMID: 37545642 PMC: 10401658. DOI: 10.3748/wjg.v29.i27.4252.

Dietary Supplementation of Ancientino Ameliorates Dextran Sodium Sulfate-Induced Colitis by Improving Intestinal Barrier Function and Reducing Inflammation and Oxidative Stress.

Liu M, Wang Y, Guan G, Lu X, Zhu Y, Duan X Nutrients. 2023; 15(12).

PMID: 37375702 PMC: 10304453. DOI: 10.3390/nu15122798.

References

Cheng L, Jin H, Qiang Y, Wu S, Yan C, Han M . High fat diet exacerbates dextran sulfate sodium induced colitis through disturbing mucosal dendritic cell homeostasis. Int Immunopharmacol. 2016; 40:1-10. DOI: 10.1016/j.intimp.2016.08.018. View

Kumar S, Kumar A . Microbial pathogenesis in inflammatory bowel diseases. Microb Pathog. 2022; 163:105383. DOI: 10.1016/j.micpath.2021.105383. View

Targan S, Karp L . Defects in mucosal immunity leading to ulcerative colitis. Immunol Rev. 2005; 206:296-305. DOI: 10.1111/j.0105-2896.2005.00286.x. View

Mirsepasi-Lauridsen H, Vallance B, Krogfelt K, Petersen A . Pathobionts Associated with Inflammatory Bowel Disease. Clin Microbiol Rev. 2019; 32(2). PMC: 6431131. DOI: 10.1128/CMR.00060-18. View

Sokol H, Leducq V, Aschard H, Pham H, Jegou S, Landman C . Fungal microbiota dysbiosis in IBD. Gut. 2016; 66(6):1039-1048. PMC: 5532459. DOI: 10.1136/gutjnl-2015-310746. View

Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L . A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice. Nat Med. 2016; 23(1):107-113. DOI: 10.1038/nm.4236. View

Aniwan S, Tremaine W, Raffals L, Kane S, Loftus Jr E . Antibiotic Use and New-Onset Inflammatory Bowel Disease in Olmsted County, Minnesota: A Population-Based Case-Control Study. J Crohns Colitis. 2017; 12(2):137-144. PMC: 5881749. DOI: 10.1093/ecco-jcc/jjx135. View

Jugder B, Kamareddine L, Watnick P . Microbiota-derived acetate activates intestinal innate immunity via the Tip60 histone acetyltransferase complex. Immunity. 2021; 54(8):1683-1697.e3. PMC: 8363570. DOI: 10.1016/j.immuni.2021.05.017. View

Duerr R . The genetics of inflammatory bowel disease. Gastroenterol Clin North Am. 2002; 31(1):63-76. DOI: 10.1016/s0889-8553(01)00005-x. View

10.

Jostins L, Ripke S, Weersma R, Duerr R, McGovern D, Hui K . Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 2012; 491(7422):119-24. PMC: 3491803. DOI: 10.1038/nature11582. View

11.

Khademi Z, Milajerdi A, Larijani B, Esmaillzadeh A . Dietary Intake of Total Carbohydrates, Sugar and Sugar-Sweetened Beverages, and Risk of Inflammatory Bowel Disease: A Systematic Review and Meta-Analysis of Prospective Cohort Studies. Front Nutr. 2021; 8:707795. PMC: 8517080. DOI: 10.3389/fnut.2021.707795. View

12.

Hou J, Abraham B, El-Serag H . Dietary intake and risk of developing inflammatory bowel disease: a systematic review of the literature. Am J Gastroenterol. 2011; 106(4):563-73. DOI: 10.1038/ajg.2011.44. View

13.

Brant S, Wang M, Rawsthorne P, Sargent M, Datta L, Nouvet F . A population-based case-control study of CARD15 and other risk factors in Crohn's disease and ulcerative colitis. Am J Gastroenterol. 2006; 102(2):313-23. DOI: 10.1111/j.1572-0241.2006.00926.x. View

14.

Brant S . Update on the heritability of inflammatory bowel disease: the importance of twin studies. Inflamm Bowel Dis. 2010; 17(1):1-5. DOI: 10.1002/ibd.21385. View

15.

Yoon S, Lee J, Lee J, Na G, Lee K, Lee Y . Low-FODMAP formula improves diarrhea and nutritional status in hospitalized patients receiving enteral nutrition: a randomized, multicenter, double-blind clinical trial. Nutr J. 2015; 14:116. PMC: 4632275. DOI: 10.1186/s12937-015-0106-0. View

16.

Rychter A, Ratajczak A, Zawada A, Dobrowolska A, Krela-Kazmierczak I . Non-Systematic Review of Diet and Nutritional Risk Factors of Cardiovascular Disease in Obesity. Nutrients. 2020; 12(3). PMC: 7146494. DOI: 10.3390/nu12030814. View

17.

Ajabnoor S, Thorpe G, Abdelhamid A, Hooper L . Long-term effects of increasing omega-3, omega-6 and total polyunsaturated fats on inflammatory bowel disease and markers of inflammation: a systematic review and meta-analysis of randomized controlled trials. Eur J Nutr. 2020; 60(5):2293-2316. DOI: 10.1007/s00394-020-02413-y. View

18.

Burisch J, Pedersen N, Cukovic-Cavka S, Turk N, Kaimakliotis I, Duricova D . Environmental factors in a population-based inception cohort of inflammatory bowel disease patients in Europe--an ECCO-EpiCom study. J Crohns Colitis. 2013; 8(7):607-16. DOI: 10.1016/j.crohns.2013.11.021. View

19.

Radford-Smith G, Edwards J, Purdie D, Pandeya N, Watson M, Martin N . Protective role of appendicectomy on onset and severity of ulcerative colitis and Crohn's disease. Gut. 2002; 51(6):808-13. PMC: 1773455. DOI: 10.1136/gut.51.6.808. View

20.

Schaubeck M, Clavel T, Calasan J, Lagkouvardos I, Haange S, Jehmlich N . Dysbiotic gut microbiota causes transmissible Crohn's disease-like ileitis independent of failure in antimicrobial defence. Gut. 2015; 65(2):225-37. PMC: 4752651. DOI: 10.1136/gutjnl-2015-309333. View