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One-Stage Coverage of Leg Region Defects with STSG Combined with VAC Dressing Improves Early Patient Mobilisation and Graft Take: A Comparative Study

Overview
Journal J Clin Med
Specialty General Medicine
Date 2022 Jun 24
PMID 35743375
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Abstract

Lower limb skin defects are very common and can result from a wide range of aetiologies. Split thickness skin graft (STSG) is a widely used method to address these problems. The role of postoperative dressing is primary as it permits one to apply a uniform pressure over the grafted area and promote adherence. Focusing on lower limb reconstruction, our clinical study compares the application of V.A.C. (Vacuum Assisted Closure) Therapy vs. conventional dressing in the immediate postoperative period following skin grafting. We included in the study all patients who received skin grafts on the leg region between January 2015 and December 2018, despite the aetiology of the defect. Only reconstructions with complete preoperative and postoperative follow-up data were included in the study. Patients were divided into two groups depending on if they received a traditional compressive dressing or a VAC dressing in the immediate postoperative period. We could retain 92 patients, 23 in the No VAC group and 69 in the VAC group. The patients included in the VAC group showed a statistically significant higher rate of graft take together with a lower immobilisation time (p < 0.05). Moreover, a lower rate of postoperative infection was recorded in the VAC group. This study represents the largest in the literature to report in detail surgical outcomes comparing the use of VAC therapy vs. conventional dressing after STSG in the postoperative management of lower limb reconstruction using skin grafts. VAC therapy was used to secure the grafts in the leg region, increasing the early graft take rate while at the same time improving patient mobilisation.

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References
1.
Maruccia M, Onesti M, Sorvillo V, Albano A, Dessy L, Carlesimo B . An Alternative Treatment Strategy for Complicated Chronic Wounds: Negative Pressure Therapy over Mesh Skin Graft. Biomed Res Int. 2017; 2017:8395219. PMC: 5337327. DOI: 10.1155/2017/8395219. View

2.
Saxena V, Hwang C, Huang S, Eichbaum Q, Ingber D, Orgill D . Vacuum-assisted closure: microdeformations of wounds and cell proliferation. Plast Reconstr Surg. 2004; 114(5):1086-96. DOI: 10.1097/01.prs.0000135330.51408.97. View

3.
Carson S, Overall K, Lee-Jahshan S, Travis E . Vacuum-assisted closure used for healing chronic wounds and skin grafts in the lower extremities. Ostomy Wound Manage. 2004; 50(3):52-8. View

4.
Korber A, Franckson T, Grabbe S, Dissemond J . Vacuum assisted closure device improves the take of mesh grafts in chronic leg ulcer patients. Dermatology. 2008; 216(3):250-6. DOI: 10.1159/000112937. View

5.
Ross R, Aflaki P, Gendics C, Lantis Ii J . Complex lower extremity wounds treated with skin grafts and NPWT: a retrospective review. J Wound Care. 2011; 20(10):490, 492-5. DOI: 10.12968/jowc.2011.20.10.490. View